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06855

Sigma-Aldrich

Kollisolv® PEG E 400

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Synonym(s):
Poly(ethylene glycol), Lutrol® E 400, Macrogol 400, Polyethylene glycol 400, PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
NACRES:
NA.25

form

liquid

mol wt

average Mw 380-420 g/mol (from OH-value (56100*2/OHZ))

technique(s)

electrophoresis: suitable

impurities

reducing substances, complies
≤0.1% sulfated ash
≤0.25% ethylene glycol and diethylene glycol (sum)
≤0.5 g acetic acid (per 100 g)
≤1 ppm ethylene oxide
≤1 ppm lead (verified on random samples only)
≤1.0% water
≤10 ppm dioxan
≤15 ppm formaldehyde
≤5 ppm heavy metals (verfied on random samples only)
≤620 ppm ethylene glycol

pH

4.5-7.0 (50 g/L)

viscosity

105-130 mPa.s(20 °C) (6.8-8.0 CS (98.9°C)

hydroxyl value

267‑295 mg KOH/g

solubility

H2O: 10%, clear, colorless

suitability

complies for acidity or alkalinity

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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1 of 4

This Item
81172PX1286B8.07485
vibrant-m

06855

Kollisolv® PEG E 400

vibrant-m

81172

Poly(ethylene glycol)

vibrant-m

PX1286B

Polyethylene glycol

vibrant-m

8.07485

Polyethylene glycol

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

impurities

reducing substances, complies, ≤0.25% ethylene glycol and diethylene glycol (sum), ≤1 ppm ethylene oxide, ≤1.0% water, ≤15 ppm formaldehyde, ≤620 ppm ethylene glycol, ≤0.1% sulfated ash, ≤1 ppm lead (verified on random samples only), ≤5 ppm heavy metals (verfied on random samples only), ≤0.5 g acetic acid (per 100 g), ≤10 ppm dioxan

impurities

-

impurities

-

impurities

-

mol wt

average Mw 380-420 g/mol (from OH-value (56100*2/OHZ))

mol wt

380-420

mol wt

-

mol wt

-

technique(s)

electrophoresis: suitable

technique(s)

-

technique(s)

-

technique(s)

-

pH

4.5-7.0 (50 g/L)

pH

-

pH

5-7 (20 °C, 100 g/L in H2O, neutral)

pH

5-7 (20 °C, 100 g/L in H2O)

Application

Kollisolv polyethylene glycols are used as thickening agents and gel binders in the pharmaceutical industry.
This research grade product is intended for use in R&D and development only.

Other Notes

The PEG E grades of Kollisolv are polyethylene glycols (macrogols) of different molecular weights.

Legal Information

Kollisolv is a registered trademark of BASF
Lutrol is a registered trademark of BASF SE

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro

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