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PHR1369

Supelco

Thiamine pyrophosphate

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Thiamine pyrophosphate, Aneurinepyrophosphoric acid, Cocarboxylase, Thiamine pyrophosphate chloride
Empirical Formula (Hill Notation):
C12H19ClN4O7P2S
CAS Number:
Molecular Weight:
460.77
Beilstein/REAXYS Number:
3875902
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1656002

API family

thiamine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

SMILES string

CC1=C(CCOP(OP(O)(O)=O)(O)=O)SC=[N+]1CC2=C(N)N=C(C)N=C2.[Cl-]

InChI

1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H

InChI key

YXVCLPJQTZXJLH-UHFFFAOYSA-N

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1 of 4

This Item
C8754PHR2207PHR1337
Thiamine pyrophosphate Pharmaceutical Secondary Standard; Certified Reference Material

PHR1369

Thiamine pyrophosphate

Thiamine pyrophosphate ≥95%

C8754

Thiamine pyrophosphate

Supelco

PHR2207

Thiamine Thiocarbamate

Thiamine Nitrate Pharmaceutical Secondary Standard; Certified Reference Material

PHR1337

Thiamine Nitrate

format

neat

format

-

format

-

format

neat

Quality Level

300

Quality Level

-

Quality Level

300

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

storage temp.

-10 to -25°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

agency

traceable to USP 1656002

agency

-

agency

-

agency

traceable to BP 414, traceable to Ph. Eur. Y0000060

General description

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiamine pyrophosphate is a coenzyme of transketolase that catalyzes the cleavage of ribulose-5-phosphate; thereby forming D-glyceraldehyde-3-phosphate. This reaction requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde.

application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA1473 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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J Ullrich et al.
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