T8637

Thiamine monophosphate chloride dihydrate

• Synonym(s): Aneurine monophosphate chloride
• Empirical Formula (Hill Notation): C₁₂H₁₈ClN₄O₄PS · 2H₂O
• CAS Number: 273724-21-3
• Molecular Weight: 416.82
• Beilstein/REAXYS Number: 3844977
• EC Number: 208-536-9
• MDL number: MFCD00063473
• UNSPSC Code: 12352107
• PubChem Substance ID: 24900546
• NACRES: NA.79

Properties

• biological source: synthetic
• Quality Level: 200
• assay: ≥99.0% (HPLC)
• form: powder
• technique(s): HPLC: suitable
• color: white to off-white
• mp: 190 °C
• storage temp.: 2-8°C
• SMILES string: [Cl-].Cc1ncc(C[n+]2csc(CCOP(O)(O)=O)c2C)c(N)n1
• InChI: 1S/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H
• InChI key: GUGWNSHJDUEHNJ-UHFFFAOYSA-N

Description

Application

Thiamine monophosphate chloride dihydrate has been used as a standard in high-performance liquid chromatography (HPLC) to quantify thiamine in plant exudates and to evaluate its purity.

Biochem/physiol Actions

Thiamine monophosphate (TMP) is used as a substrate of thiamine-phosphate kinase (EC 2.7.4.16) and a precursor of thiamine pyrophosphate (TPP). TPP is a coenzyme involved in the catabolism of sugars and amino acids.

Thiamine monophosphate (TMP) is used as a substrate of thiamine-phosphate kinase (EC 2.7.4.16) and a precursor of thiamine pyrophosphate (TPP). TPP is a coenzyme involved in the catabolism of sugars and amino acids. TMP acts as an intermediate in the hydrolysis of thiamine pyrophosphate to thiamine.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)