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Q5001

Supelco

Quinidine gluconate salt

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H24N2O2 · C6H12O7
CAS Number:
7054-25-3
Molecular Weight:
520.57
EC Number:
230-333-9
MDL number:
MFCD00067566
UNSPSC Code:
41116107
PubChem Substance ID:
329823867
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

application(s)

food and beverages

format

neat

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.[H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H24N2O2.C6H12O7/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;7-1-2(8)3(9)4(10)5(11)6(12)13/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2-5,7-11H,1H2,(H,12,13)/t13-,14-,19+,20-;2-,3-,4+,5-/m01/s1

InChI key

XHKUDCCTVQUHJQ-LCYSNFERSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Class IA antiarrhythmic; potassium channel blocker.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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K D Miller et al.
The New England journal of medicine, 321(2), 65-70 (1989-07-13)
During the past decade the incidence of Plasmodium falciparum malaria in the United States has increased 10-fold. Treatment may be delayed because the therapy recommended for severe or complicated disease, intravenous quinine dihydrochloride, is available only from the Centers for
Proarrhythmia: disparity of programmed electrical stimulation results and spontaneous occurrence: a case report.
A E Alicea et al.
Maryland medical journal (Baltimore, Md. : 1985), 40(6), 521-523 (1991-06-01)
D J Weiss et al.
Journal of the American Veterinary Medical Association, 196(3), 472-475 (1990-02-01)
Records of 8 dogs with drug-associated aplastic anemia were reviewed. Drugs suspected as being causative included estradiol cyclopentylpropionate (3 dogs), phenylbutazone (2 dogs), meclofenamic acid (1 dog), trimethoprim-sulfadiazine and fenbendazole (1 dog), and quinidine (1 dog). Five of the dogs
P T Holzberger et al.
American heart journal, 136(1), 49-56 (1998-07-17)
Intravenous procainamide hydrochloride is frequently used in the acute care setting and during electrophysiologic testing, but intravenous quinidine gluconate is rarely used because of concerns about its safety. This study prospectively compares the hemodynamic and electrophysiologic effects of these agents
A Garg et al.
Journal of cardiovascular electrophysiology, 9(6), 642-647 (1998-07-08)
A case is presented of an 18-year-old male who had been resuscitated following an episode of sudden death due to ventricular fibrillation. The patient was noted to have an abnormal deflection in the terminal QRS on surface ECG and an
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