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greener alternative

average Mn ~1,150

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BRIJ® O20, Polyoxyethylene (20) oleyl ether
Linear Formula:
C18H35(OCH2CH2)nOH, n~20
CAS Number:
Molecular Weight:
MDL number:



Quality Level



mol wt

average Mn ~1,150

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.


25-30 °C (lit.)

hydroxyl value

50‑65 mg KOH/g



greener alternative category



InChI key


General description

ECO Brij® O20, also known as oleyl alcohol polyoxyethylene ether, is a bio-based, high HLB nonionic surfactant manufactured from naturally occurring straight-chain oleyl alcohol. This detergent, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting, making it suitable for a range of applications in biochemical and biological research.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".

Features and Benefits

  • 100 % Renewable
  • 100 % Bio-based
  • Certified to the USDA BioPreferred Program
  • Lower carbon footprint than petrochemical-based versions
  • High-purity chemical suitable for a wide variety of research applications

Legal Information

Brij is a registered trademark of Croda International PLC
ECO BRIJ is a registered trademark of Croda Inc.


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Signal Word


Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids



Flash Point(F)

464.0 °F - Equilibrium method

Flash Point(C)

> 240 °C - Equilibrium method

Certificates of Analysis (COA)

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Yash Kapoor et al.
International journal of pharmaceutics, 361(1-2), 222-229 (2008-06-26)
Cyclosporine A (CyA) is an immunosuppressant drug that is used for treating a variety of ocular diseases and disorders. CyA is commonly delivered via eye drops, which is highly inefficient due to a low bioavailability of less than 5%. The
Majid Tabbakhian et al.
International journal of pharmaceutics, 323(1-2), 1-10 (2006-07-14)
Finasteride is indicated orally in the treatment of androgenetic alopecia and some other pilosebaceous unit (PSU) disorders. We wished to investigate whether topical application of finasteride-containing vesicles (liposomes and niosomes) could enhance drug concentration at the PSU, as compared to
Doaa Ahmed El-Setouhy et al.
The Journal of pharmacy and pharmacology, 62(1), 25-34 (2010-08-21)
The objective of this study was to improve systemic delivery of the highly analgesic ketorolac trometamol (ketorolac tromethamine) via the transdermal route, through cost-effective topical formulations, to avoid most of the problems associated with ketorolac trometamol therapy. In-vitro release behaviour
Sergey Filippov et al.
Langmuir : the ACS journal of surfaces and colloids, 24(17), 9295-9301 (2008-08-09)
In this work we report a new type of pH-responsive micelle-like nanoparticle. Reversible nanoscale structures are formed in solutions of a pH-sensitive hydrophobic polyelectrolyte, poly( N-methacryloyl- l-valine) or poly( N-methacryloyl- l-phenylalanine), and nonionic surfactant (Brij 98) in the presence of
Carles Gil et al.
Biochemical and biophysical research communications, 348(4), 1334-1342 (2006-08-22)
Although the high presence of cholesterol in nerve terminals is well documented, specific roles of this lipid in transmitter release have remained elusive. Since cholesterol is a highly enriched component in the membrane microdomains known as lipid rafts, it is

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