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Sigma-Aldrich

Brij® S 100

average Mn ~4,670

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Synonym(s):
Polyoxyethylene (100) stearyl ether
Linear Formula:
C18H37(OCH2CH2)nOH, n~100
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

mol wt

average Mn ~4,670

Quality Level

mp

51-54 °C (lit.)

hydroxyl value

13‑25 mg KOH/g

solubility

propylene glycol and xylene: insoluble

density

1.1 g/mL at 25 °C (lit.)

HLB

18

InChI

1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3

InChI key

PSEGVHKUPXNGGJ-UHFFFAOYSA-N

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Application

Brij® S 100 may be used:
  • as a non-ionic surfactant to study its interactions with luminol electrochemiluminescence for bioanalysis
  • as a carrier material to study the formulation of nimodipine, fenofibrate, and o-vanillin using the particles from gas-saturated solution (PGSS) process
  • as a hydrophilic surfactant in the casting solution to prepare an asymmetric flat sheet nanofiltration membranes and to study its effects on the hydrophilic property of the poly(ethersulfone) (PES) nanofiltration membranes

Legal Information

Brij is a registered trademark of Croda International PLC

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Formulation of nimodipine, fenofibrate, and o-vanillin with Brij S100 and PEG 4000 using the PGSS process
Kravanja G, et al.
Journal of Supercritical Fluids, 135, 245-253 (2018)
Lingyan Song et al.
Journal of colloid and interface science, 328(2), 374-384 (2008-10-17)
Patternable nanoporous silica thin films with pore sizes on multiple length scales are fabricated using preformed block copolymer/homopolymer blend films as templates. Previous work by Tirumala et al. [V.R. Tirumala, R.A. Pai, S. Agarwal, J.J. Testa, G. Bhatnagar, A.H. Romang
S Rahima Benhabbour et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(1), 63-71 (2011-11-01)
Lipid-based oil-filled nanoparticles (NPs) with a high concentration of surface-chelated nickel (Ni-NPs) were successfully prepared using a Brij 78-NTA-Ni conjugate synthesized with Brij 78 (Polyoxyethylene (20) stearyl ether) and nitrilotriacetic acid (NTA). The facile incorporation of the Brij 78-NTA-Ni conjugate
Jae-Haeng Song et al.
Drug development and industrial pharmacy, 35(8), 897-903 (2009-02-26)
The oral administration of loratadine, an antihistamine, can have a variety of adverse side effects, such as headache, fatigue, and nausea, because of the transient high blood concentration. To avoid these effects, loratadine can be administered using a transdermal drug
S O Williams et al.
Drug development and industrial pharmacy, 26(1), 71-77 (2000-04-01)
The purpose of this study was to scale up an oil/water (o/w) cream formulation containing 40% diethylene glycol monoethyl ether (DGME), developed via 300-g laboratory batches in a 2(5-2) fractional factorial design, to 7-kg batch sizes in a Brogli-10 homogenizer.

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