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388890

Brij® S10

average Mn ~711

Synonym(s):

Polyethylene glycol octadecyl ether, Polyoxyethylene (10) stearyl ether

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About This Item

Linear Formula:
C18H37(OCH2CH2)nOH, n~10
CAS Number:
9005-00-9
UNSPSC Code:
12162002
PubChem Substance ID:
24864250
NACRES:
NA.23
MDL number:
MFCD00074177

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SMILES string

O(CC[O])CCCCCCCCCCCCCCCCCC

InChI

1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3

InChI key

PSEGVHKUPXNGGJ-UHFFFAOYSA-N

mol wt

average Mn ~711

mp

37-39 °C (lit.)

density

0.964 g/mL at 25 °C (lit.)

HLB

12

Quality Level

100

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Legal Information

Brij is a registered trademark of Croda International PLC

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ1735
BCBR0852V
BCBJ0791V
BCBD7589V
1435704

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Anne Huhtala et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 19(1), 11-21 (2003-03-22)
This study was undertaken to investigate the use of the in vitro test WST-1, an assay of cell proliferation and viability, for a preliminary safety evaluation of topical ophthalmic preparations. The cytotoxicity of two surfactants, benzalkonium chloride (BAC) and polyoxyethylene-20-stearyl
Tatsuaki Tagami et al.
Journal of controlled release : official journal of the Controlled Release Society, 161(1), 142-149 (2012-04-17)
Here we report the development of an enhanced thermosensitive formulation composed of DPPC and Brij78, loaded with doxorubicin (DOX) using a Cu²⁺ gradient and post-inserted with an additional amount of Brij78. This optimal formulation (HaT-II: Hyperthermia-activated cytoToxic) displayed significantly improved
Joanna M Koziara et al.
Journal of controlled release : official journal of the Controlled Release Society, 99(2), 259-269 (2004-09-24)
Despite the advances in tumor therapy, patients with primary brain tumors and brain metastases have a very poor prognosis. Low responses to chemotherapy are mainly attributed to impermeability of the blood-brain barrier to cytotoxic agents. Paclitaxel has been shown to
Jae-Haeng Song et al.
Drug development and industrial pharmacy, 35(8), 897-903 (2009-02-26)
The oral administration of loratadine, an antihistamine, can have a variety of adverse side effects, such as headache, fatigue, and nausea, because of the transient high blood concentration. To avoid these effects, loratadine can be administered using a transdermal drug
J Q Zhang et al.
Drug delivery, 14(6), 381-387 (2007-08-19)
The study describes the development of stealth solid lipid nanoparticles (SLNs) as colloidal carriers for silibinin, a drug with very low solubility. Stealth SLNs were constituted mainly of bioacceptable and biodegradable lipids, such as stearic acid and surfactant Brij 78
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