MilliporeSigma
All Photos(1)

338826

Sigma-Aldrich

Acetic acid

glacial, ≥99.99% trace metals basis

Sign Into View Organizational & Contract Pricing

Select a Size

Synonym(s):
Glacial acetic acid
Linear Formula:
CH3CO2H
CAS Number:
Molecular Weight:
60.05
Beilstein:
506007
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Agency

suitable for ASTM® 7969
suitable for ASTM® 7979
suitable for DIN 38407-43
suitable for EPA 1634
suitable for EPA 534
suitable for EPA 8328
suitable for EPA ACB B21-03
suitable for ISO 21675 2019
suitable for ISO 25101
suitable for ISO/CEN 15968-2011

Quality Level

vapor density

2.07 (vs air)

Assay

≥99.99% trace metals basis

form

liquid

autoignition temp.

800 °F

expl. lim.

16 %, 92 °F
4 %, 59 °F

technique(s)

HPLC: suitable

refractive index

n20/D 1.371 (lit.)

pH

2.5 (20 °C, 50 g/L)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

density

1.049 g/mL at 25 °C (lit.)

SMILES string

CC(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

InChI key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
AX007327221137130
Acetic acid glacial, ≥99.99% trace metals basis

Sigma-Aldrich

338826

Acetic acid

Acetic Acid, Glacial Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS

Supelco

AX0073

Acetic Acid, Glacial

Acetic acid glacial, puriss., 99-100%

Sigma-Aldrich

27221

Acetic acid

Acetic acid, glacial EMPROVE® EXPERT, Ph. Eur., JP, USP

SAFC

137130

Acetic acid, glacial

assay

≥99.99% trace metals basis

assay

-

assay

99-100%

assay

-

form

liquid

form

liquid

form

liquid

form

liquid

refractive index

n20/D 1.371 (lit.)

refractive index

n20/D 1.371 (lit.)

refractive index

n20/D 1.371 (lit.)

refractive index

n20/D 1.371 (lit.)

pH

2.5 (20 °C, 50 g/L)

pH

2.5 (20 °C, 50 g/L in H2O)

pH

2.5 (20 °C, 50 g/L)

pH

-

bp

117-118 °C (lit.)

bp

117-118 °C (lit.)

bp

117-118 °C (lit.)

bp

117-118 °C (lit.)

Application

Acetic acid can be used as a catalyst:
  • For the solvent-free one-pot condensation of indoles with aryl or heteroaryl aldehydes to synthesize di(indolyl)methanes.
  • In the Pictet-Spengler reaction of substituted tryptamines with cyclic ketones to synthesize tetrahydrospiro-Ͱ-carbolines.
  • To synthesize trisubstituted thiazoles via domino multicomponent reaction.

It can also be used as a:
  • solvent to synthesize aryl amine-functionalized 1,3,5-triazine derivatives via aryl amination of cyanuric chloride with aromatic amines.

Legal Information

ASTM is a registered trademark of American Society for Testing and Materials

Pictograms

FlameCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

102.2 °F

Flash Point(C)

39 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 5

1 of 5

Acetic acid natural, ≥99.5%, FG

Sigma-Aldrich

W200603

Acetic acid

Glacial acetic acid United States Pharmacopeia (USP) Reference Standard

USP

1005706

Glacial acetic acid

Acetic acid (glacial) 100% Suprapur®

Supelco

1.00066

Acetic acid (glacial) 100%

Glacial Acetic Acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1748

Glacial Acetic Acid

Acetic acid 100% for HPLC LiChropur™

Supelco

5.43808

Acetic acid 100%

Isabelle Brunet et al.
The Journal of clinical investigation, 124(7), 3230-3240 (2014-06-18)
Autonomic sympathetic nerves innervate peripheral resistance arteries, thereby regulating vascular tone and controlling blood supply to organs. Despite the fundamental importance of blood flow control, how sympathetic arterial innervation develops remains largely unknown. Here, we identified the axon guidance cue
Katharine Trenholme et al.
Antimicrobial agents and chemotherapy, 58(7), 3666-3678 (2014-04-16)
Therapies to prevent transmission of malaria parasites to the mosquito vector are a vital part of the global malaria elimination agenda. Primaquine is currently the only drug with such activity; however, its use is limited by side effects. The development
Grete Andersen et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 308(2), R123-R130 (2014-11-21)
In healthy individuals, postexercise protein supplementation increases muscle protein anabolism. In patients with muscular dystrophies, aerobic exercise improves muscle function, but the effect of exercise on muscle protein balance is unknown. Therefore, we investigated 1) muscle protein balance before, during
Janani Ramaswamy et al.
Biomaterials, 73, 120-130 (2015-09-26)
Functionalization of biomaterials with material- and cell-specific peptide sequences allows for better control of their surface properties and communication with the surrounding environment. Using a combinatorial phage display approach, we previously identified the peptide VTKHLNQISQSY (VTK) with specific affinity to
Hui Zhang et al.
Biochimica et biophysica acta, 1853(2), 470-480 (2014-12-09)
Dipeptidyl peptidase 9 (DPP9) is a ubiquitously expressed member of the DPP4 gene and protease family. Deciphering the biological functions of DPP9 and its roles in pathogenesis has implicated DPP9 in tumor biology, the immune response, apoptosis, intracellular epidermal growth

Articles

Analysis of Activated Nucleotide Sugars by LC-MS/MS

A sensitive LC-MS/MS quantitative method for the simultaneous analysis of highly polar 11 nucleotide activated sugars having similar structures and physicochemical properties using Supel™ Carbon LC column.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service