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12107C

Sigma-Aldrich

Fetal Bovine Serum

USA origin, γ-irradiated by SER-TAIN process, sterile-filtered, suitable for cell culture

Synonym(s):

Fetal Calf Sera, Fetal Calf Serum, GI FBS, GI FCS, GI Fetal Bovine Sera, GI Fetal Bovine Serum, GI Fetal Calf Serum, FBS, FCS, sera, serum

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About This Item

MDL number:
UNSPSC Code:
12352207
NACRES:
NA.71

biological source

bovine fetus

Quality Level

sterility

sterile-filtered

product line

FBS Premier

composition

hemoglobin, ≤20 mg/dL

origin

USA origin

technique(s)

cell culture | mammalian: suitable

impurities

≤10 EU/mL endotoxin

shipped in

dry ice

storage temp.

−20°C

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Application

FBS provides many non-defined growth promoting and survival enhancing factor to cells in culture.

Preparation Note

Gamma irradiation by SER-TAIN process (25-40kGy).

Analysis Note

  • Endotoxin and hemoglobin tested
  • Tested for the presence of bacteria, virus, and mycoplasma
  • Triple filtered with 0.1 micron membrane under aseptic conditions

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


Certificates of Analysis (COA)

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Yusuke Ohnishi et al.
PloS one, 3(5), e2248-e2248 (2008-05-22)
Allele-specific gene silencing by RNA interference (RNAi) is therapeutically useful for specifically inhibiting the expression of disease-associated alleles without suppressing the expression of corresponding wild-type alleles. To realize such allele-specific RNAi (ASP-RNAi), the design and assessment of small interfering RNA
Silvia Goldoni et al.
The American journal of pathology, 173(3), 844-855 (2008-08-09)
Decorin, a member of the small leucine-rich proteoglycan gene family, down-regulates members of the ErbB receptor tyrosine kinase family and attenuates their signaling, leading to growth inhibition. We investigated the effects of decorin on the growth of ErbB2-overexpressing mammary carcinoma
Feng C Zhou et al.
BMC genomics, 12, 124-124 (2011-02-23)
We have previously demonstrated that alcohol exposure at early neurulation induces growth retardation, neural tube abnormalities, and alteration of DNA methylation. To explore the global gene expression changes which may underline these developmental defects, microarray analyses were performed in a
Nan Jiang et al.
Molecular and cellular biology, 29(13), 3556-3568 (2009-04-22)
Insulator elements play a role in gene regulation that is potentially linked to nuclear organization. Boundary element-associated factors (BEAFs) 32A and 32B associate with hundreds of sites on Drosophila polytene chromosomes. We hybridized DNA isolated by chromatin immunoprecipitation to genome
Anu Sharma et al.
PloS one, 6(11), e28217-e28217 (2011-12-06)
γ-radiation is an effective treatment for cancer. There is evidence that radiotherapy supports tumor-specific immunity. It was described that irradiation induces de novo protein synthesis and enhances antigen presentation, we therefore investigated whether γ-radiation results in increased expression of cancer-testis

Articles

Find answers to questions (FAQs) about fetal bovine serum (FBS) that is gamma-irradiated by the SER-TAIN™ process. Request a sample of FBS at Sigma-Aldrich.com.

Protocols

Protect your investment with best practices for storing and thawing FBS and other sera. Sample FBS for validation in your cell culture protocol.

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