Skip to Content
MilliporeSigma
All Photos(1)

Documents

137272

SAFC

Guanidine hydrochloride

EMPROVE® EVOLVE

Pharma Manufacturing

Sign Into View Organizational & Contract Pricing

Synonym(s):
Guanidine hydrochloride, Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
Linear Formula:
NH2C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
95.53
Beilstein/REAXYS Number:
3591990
MDL number:
UNSPSC Code:
12352107

biological source

synthetic

Quality Level

product line

EMPROVE® EVOLVE

form

powder

impurities

Endotoxin, microbial, and trace metals; tested

pH

(25 °C, 4.6 - 6/573 g/L)

mp

180-185 °C (lit.)
180-185 °C (lit.)

solubility

water: 6 M at 20 °C, clear, colorless

density

1.3 g/cm3 (lit.)
1.3 g/cm3 (lit.)

suitability

suitable for manufacturing use

storage temp.

2-30°C

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

General description

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service