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50940

Sigma-Aldrich

Guanidine hydrochloride

≥99.0% (AT)

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Synonym(s):
Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
Linear Formula:
NH2C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
95.53
Beilstein:
3591990
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.55

Assay

≥99.0% (AT)

form

solid

ign. residue

≤0.1% (as SO4)

pH

(25 °C, 4.6 - 6/573 g/L)

mp

180-185 °C (lit.)

solubility

H2O: 6 M at 20 °C, clear, colorless

density

1.3 g/cm3 (lit.)

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤20 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

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This Item
5095050933G4505
Guanidine hydrochloride ≥99.0% (AT)

Sigma-Aldrich

50940

Guanidine hydrochloride

-
Guanidine hydrochloride ≥98%

Sigma-Aldrich

50950

Guanidine hydrochloride

-
Guanidine hydrochloride BioUltra, for molecular biology, ≥99.5% (AT)

Sigma-Aldrich

50933

Guanidine hydrochloride

Premium Grade
Guanidine hydrochloride ≥99% (titration), organic base and chaeotropic agent

Sigma-Aldrich

G4505

Guanidine hydrochloride

-
form

solid

form

powder or crystals

form

powder or crystals

form

crystalline powder

pH

(25 °C, 4.6 - 6/573 g/L)

pH

(25 °C, 4.6 - 6/573 g/L)

pH

4.5-6.0 (25 °C, 6 M in H2O)

pH

(25 °C, 4.6 - 6 at 573 g/L)

mp

180-185 °C (lit.)

mp

180-185 °C (lit.)

mp

180-185 °C (lit.)

mp

180-185 °C (lit.)

solubility

H2O: 6 M at 20 °C, clear, colorless

solubility

H2O: 6 M, clear (100 Hazen)

solubility

H2O: 6 M at 20 °C, clear, colorless

solubility

H2O: 6 M

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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