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27487

Sigma-Aldrich

Citric acid

BioUltra, anhydrous, ≥99.5% (T)

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Linear Formula:
HOC(COOH)(CH2COOH)2
CAS Number:
Molecular Weight:
192.12
Beilstein:
782061
EC Number:
MDL number:
eCl@ss:
39021801
PubChem Substance ID:
NACRES:
NA.25

Quality Level

product line

BioUltra

Assay

≥99.5% (T)

form

powder or crystals

expl. lim.

8 %, 65 °F

technique(s)

cell culture | hybridoma: suitable

impurities

insoluble matter, passes filter test

ign. residue

≤0.05% (as SO4)

loss

≤0.5% loss on drying, 110 °C

pH

1.0-2.0 (25 °C, 1 M in H2O)

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

mp

153-159 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤5 mg/kg
oxalate (C2O42-): ≤0.05%
phosphate (PO43-): ≤5 mg/kg
sulfate (SO42-): ≤20 mg/kg
tartrate (C4H4O62-): ≤0.20%

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λmax

260 nm (Amax: ≤0.20)
280 nm (Amax: ≤0.10)

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.20
λ: 280 nm Amax: 0.10

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

KRKNYBCHXYNGOX-UHFFFAOYSA-N

Gene Information

human ... SRC(6714)

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1 of 4

This Item
251275W230618791725
Citric acid BioUltra, anhydrous, ≥99.5% (T)

Sigma-Aldrich

27487

Citric acid

Premium Grade
Citric acid ACS reagent, ≥99.5%

Sigma-Aldrich

251275

Citric acid

-
Citric acid ≥99.5%, FCC, FG

Sigma-Aldrich

W230618

Citric acid

-
Citric acid anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99.5%

Sigma-Aldrich

791725

Citric acid

-
form

powder or crystals

form

crystals

form

powder or granules

form

crystals

impurities

insoluble matter, passes filter test

impurities

Substances carbonizable by hot sulfuric acid, passes test

impurities

-

impurities

Substances carbonizable by hot sulfuric acid, passes test

pH

1.0-2.0 (25 °C, 1 M in H2O)

pH

-

pH

-

pH

-

mp

153-159 °C (lit.)

mp

153-159 °C (lit.)

mp

153-159 °C (lit.)

mp

153-159 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

solubility

-

solubility

water: 383 g/L at 25 °C

solubility

-

General description

Citric acid is a buffer component for triple-column amino acid analysis. It is an optimal buffer for dissociation of radioiodinated antibodies from viable murine tumor cells.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R Ehrlich et al.
Journal of immunological methods, 26(4), 345-353 (1979-01-01)
Several low pH buffers were used in order to dissociate radioiodinated antibodies from sensitized living tumor cells. Three buffers were further tested for their dissociation abilities under different conditions of time and temperature, and for their influence on the eluted
T N Ferraro et al.
Analytical biochemistry, 143(1), 82-94 (1984-11-15)
A highly resolving triple-column amino acid analyzer with fluorometric detection is described. The reliability of this technique was evaluated and it was used in a baseline investigation of amino acids and related compounds in human cerebrospinal fluid (CSF). The procedure
Felix Schiele et al.
mAbs, 7(5), 871-880 (2015-06-06)
Novel oral anticoagulants are effective and safe alternatives to vitamin-K antagonists for anticoagulation therapy. However, anticoagulation therapy in general is associated with an elevated risk of bleeding. Idarucizumab is a reversal agent for the direct thrombin inhibitor, dabigatran etexilate (Pradaxa®)
Wayne B Batchelor et al.
Circulation, 106(12), 1470-1476 (2002-09-18)
The relative anti-aggregatory effects of currently prescribed platelet glycoprotein IIb/IIIa receptor antagonists during and after percutaneous coronary intervention for acute coronary syndromes have not been established. We randomized 70 acute coronary syndrome patients undergoing percutaneous coronary intervention to receive abciximab
Maria José Garcia-Fernandez et al.
Biofouling, 29(3), 261-271 (2013-02-27)
Prevention and management of wound infections receive a lot of attention, since the presence of micro-organisms interferes with the wound-healing process. The aim of this work was to use cyclodextrins (CDs) to endow hydrogels and gauzes with the ability to

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