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84959

Sigma-Aldrich

L-Serine

BioUltra, ≥99.5% (NT)

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Synonym(s):
(S)-2-Amino-3-hydroxypropionic acid
Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
105.09
Beilstein/REAXYS Number:
1721404
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product line

BioUltra

assay

≥99.5% (NT)

form

powder or crystals

optical activity

[α]20/D +13.5±0.5°, c = 5% in 5 M HCl

technique(s)

cell culture | mammalian: suitable

impurities

insoluble matter, passes filter test
≤0.3% foreign amino acids

ign. residue

≤0.1% (as SO4)

loss

≤0.1% loss on drying, 20 °C (HV)

color

white

mp

222 °C (dec.) (lit.)

solubility

1 M HCl: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤100 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.5 M in 1 M HCl

UV absorption

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

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1 of 4

This Item
S4311S4500PHR1103
vibrant-m

84959

L-Serine

Premium Grade
vibrant-m

S4311

L-Serine

-
vibrant-m

S4500

L-Serine

-
vibrant-m

PHR1103

L-Serine

-
form

powder or crystals

form

powder

form

powder

form

-

product line

BioUltra

product line

-

product line

ReagentPlus®

product line

-

assay

≥99.5% (NT)

assay

98.5-101.0%

assay

≥99% (HPLC)

assay

-

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

color

white

color

white

color

white to off-white

color

-

Biochem/physiol Actions

Precursor of glycine by serine hydroxymethyltransferase.

Other Notes

Synthesis of labels for protonation studies by Fourier Transform infrared methods; Stabilizes mung bean nuclease at pH values below seven; Amino acid spacing in isotachophoresis on polyacrylamide gel - a critical evaluation; Growth requirement of various microorganisms

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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CRC Handbook of Microbiology, 4, 1-1 (1974)
Bacteriorhodopsin: fourier transform infrared methods for studies of protonation of carboxyl groups.
G Dollinger et al.
Methods in enzymology, 127, 649-662 (1986-01-01)
Amino acid spacing in isotachophoresi; on polyacrylamide gel: a critical evaluation.
N Y Nguyen et al.
Analytical biochemistry, 94(1), 202-210 (1979-04-01)
Theory of protein solubility.
T Arakawa et al.
Methods in enzymology, 114, 49-77 (1985-01-01)
Kenji Hashimoto et al.
Progress in neuro-psychopharmacology & biological psychiatry, 29(5), 767-769 (2005-06-09)
Several lines of evidence suggest that D-serine, an endogenous agonist of the glycine site on the NMDA receptors, might play a role in the pathophysiology of schizophrenia. The purpose of this study was to determine whether levels of D- and

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