Skip to Content
Merck
All Photos(1)

Key Documents

90101

Sigma-Aldrich

Ampliflu Red

for fluorescence, ≥98.0% (HPLC)

Synonym(s):

10-Acetyl-3,7-dihydroxyphenoxazine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C14H11NO4
CAS Number:
Molecular Weight:
257.24
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.32

Pricing and availability is not currently available.

grade

for fluorescence

Quality Level

assay

≥98.0% (HPLC)

form

powder

fluorescence

λex 571 nm; λem 585 nm in DMSO

storage temp.

2-8°C

SMILES string

CC(=O)N1c2ccc(O)cc2Oc3cc(O)ccc13

InChI

1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3

InChI key

PKYCWFICOKSIHZ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Ampliflu Red has been used to study mitochondrial abnormalities and oxidative stress related to Parkinson’s Disease.[1] Ampliflu Red assay was suitable as an alternative indicator assay for detecting the inhibition of hTPO (human thyroid peroxidase) activity.[2] Phospholipase D, an essential cellular process ingredient, used Ampliflu Red (10-Acetyl-3,7-dihydroxyphenoxazine) to determine its activity.[3]Ampliflu Red is used for the following applications:
  • Quantification of inflammatory mediators[4]
  • Determination of free and esterified cholesterol contents[5]
  • Evaluation of compounds as substrates for GABA-AT compounds[6]

Legal Information

Ampliflu is a trademark of Sigma-Aldrich Co. LLC

related product

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Barae Jomaa et al.
ALTEX, 32(3), 191-200 (2015-03-31)
A simple and rapid luminometric assay for the detection of chemical inhibitors of human thyroid peroxidase (hTPO) activity was developed and validated with 10 model compounds. hTPO was derived from the human thyroid follicular cell line Nthy-ori 3-1 and its
Anne H van der Spek et al.
Endocrine connections, 6(8), 731-740 (2017-11-05)
Innate immune cells have recently been identified as novel thyroid hormone (TH) target cells in which intracellular TH levels appear to play an important functional role. The possible involvement of TH receptor alpha (TRα), which is the predominant TR in
Jéssie Haigert Sudati et al.
Neurotoxicology, 37, 118-126 (2013-05-04)
In this study, we investigated the potential protective effects of Valeriana officinalis (V. officinalis) against the toxicity induced by rotenone in Drosophila melanogaster (D. melanogaster). Adult wild-type flies were concomitantly exposed to rotenone (500 μM) and V. officinalis aqueous extract
Houjuan Zhu et al.
ACS nano, 11(9), 8998-9009 (2017-08-26)
Development of optical nanotheranostics for the capability of photodynamic therapy (PDT) provides opportunities for advanced cancer therapy. However, most nanotheranostic systems fail to regulate their generation levels of reactive oxygen species (ROS) according to the disease microenvironment, which can potentially
Yu Ji et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 24(63), 16865-16872 (2018-08-29)
Cetyl-trimethylammonium bromide (CTAB) is a widely used cationic surfactant that is biodegradable in nature. CTAB biodegradation requires hydroxylation in the first step, which is rate-limiting and crucial for solubility in water. In this study, the OmniChange multi-site mutagenesis method was

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service