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A2142

Sigma-Aldrich

N-Acetyl-α-D-glucosamine 1-phosphate disodium salt

≥95% (TLC)

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Linear Formula:
C8H14NO9PNa2
CAS Number:
Molecular Weight:
345.15
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥95% (TLC)

form

powder

impurities

≤9% water (Karl Fischer)

color

white

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 10.0-14.0% (Dry basis)
P: 8.0-9.6% (dry basis)

storage temp.

−20°C

SMILES string

[Na].CC(=O)NC1C(O)C(O)C(CO)OC1OP(O)(O)=O

InChI

1S/C8H16NO9P.Na.H/c1-3(11)9-5-7(13)6(12)4(2-10)17-8(5)18-19(14,15)16;;/h4-8,10,12-13H,2H2,1H3,(H,9,11)(H2,14,15,16);;

InChI key

VFEAQNOAPUQCLS-UHFFFAOYSA-N

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This Item
G6750G6875G9753
α-D-Glucose 1-phosphate dipotassium salt hydrate ≥99% (HPLC), BioXtra

G6750

α-D-Glucose 1-phosphate dipotassium salt hydrate

Premium Grade
α-D-Glucosamine 1-phosphate

G9753

α-D-Glucosamine 1-phosphate

-
solubility

water: 50 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear, colorless

solubility

water: slightly soluble 50 g/L

solubility

water: 100 mg/mL, clear, colorless

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

-

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

impurities

≤9% water (Karl Fischer)

impurities

glucose and starch, essentially free

impurities

glucose, essentially free

impurities

<8.5% water (Karl Fischer)

General description

N-Acetyl-D-glucosamine 1-phosphate (GlcNAc-1P) acts as a substrate for UDP-GlcNAc pyrophosphorylase to synthesize UDP-GlcNAc in the presence of UTP. GlcNAc-1P is a product of reverse pyrophosphorolysis of UDP-GlcNAc catalyzed by UDP-GlcNAc pyrophosphorylase.

Application

N-Acetyl-α-D-glucosamine 1-phosphate disodium salt has been used as a component of substrate solution for nucleotide triphosphate (NTP) transferases.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor
Raimi OG, et al.
RSC medicinal chemistry, 1(1), 13-25 (2020)
Measurement of Nucleotide Triphosphate Sugar Transferase Activity via Generation of Pyrophosphate
Maeda K, et al.
2013 Nurse's Drug Handbook, 5(8), e1450-e1450 (2015)
Alexandra Deli et al.
The FEBS journal, 277(13), 2740-2753 (2010-05-25)
The genomes of Bacillus cereus and its closest relative Bacillus anthracis each contain two LmbE protein family homologs: BC1534 (BA1557) and BC3461 (BA3524). Only a few members of this family have been biochemically characterized including N-acetylglucosaminylphosphatidyl inositol (GlcNAc-PI), 1-D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins)

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