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A6075

Sigma-Aldrich

Monoclonal Anti-Chicken Egg Albumin (Ovalbumin) antibody produced in mouse

clone OVA-14, ascites fluid

Synonym(s):

Anti-Albumin, chicken egg

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About This Item

MDL number:
MFCD00162221
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

OVA-14, monoclonal

mol wt

antigen 45 kDa

contains

15 mM sodium azide

species reactivity

chicken, turkey

should not react with

mouse, bovine, horse, canine, feline, pig, pigeon, rabbit, guinea pig, goat, sheep, donkey, rat, human

technique(s)

dot blot: suitable
indirect ELISA: 1:10,000 using chicken egg albumin (ovalbumin)
western blot: suitable

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

chicken ... Alb(396197)

General description

Monoclonal Anti-Chicken Egg Albumin (Ovalbumin) (mouse IgG1 isotype) is produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

Immunogen

chicken egg albumin.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Monoclonal Anti-Chicken Egg Albumin (Ovalbumin) antibody produced in mouse.

Biochem/physiol Actions

Ovalbumin (OVA) is the main component of egg white proteins in hens. OVA stimulates IgE-mediated hypersensitivity responses in individuals with egg allergy. The protein has also been used to study structure-function relationships in allergens. Thus, Monoclonal Anti-Chicken Egg Albumin (Ovalbumin) antibody can be a useful tool for the analysis of egg albumin function in mediating food allergies.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S Sheng et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(2), 499-504 (1998-01-22)
The maspin protein has tumor suppressor activity in breast and prostate cancers. It inhibits cell motility and invasion in vitro and tumor growth and metastasis in nude mice. Maspin is structurally a member of the serpin (serine protease inhibitors) superfamily
J P Zhao et al.
Journal of animal physiology and animal nutrition, 100(5), 876-883 (2016-06-09)
Three trials were performed to evaluate the association of ovalbumin (OVA) abundance in the oviduct magnum with egg production and the underlying regulatory mechanism by glucocorticoids. In trial 1, twenty Hy-Line Brown layers (56-60 weeks of age) with different combinations (n = 5/combination)
Stefan Hutzler et al.
Scientific reports, 7(1), 16892-16892 (2017-12-06)
Recombinant vaccine strain-derived measles virus (MV) is clinically tested both as vaccine platform to protect against other pathogens and as oncolytic virus for tumor treatment. To investigate the potential synergism in anti-tumoral efficacy of oncolytic and vaccine properties, we chose
Scott M Krummey et al.
Journal of immunology (Baltimore, Md. : 1950), 192(5), 2495-2504 (2014-02-05)
Effector and memory T cells may cross-react with allogeneic Ags to mediate graft rejection. Whereas the costimulation properties of Th1 cells are well studied, relatively little is known about the costimulation requirements of microbe-elicited Th17 cells. The costimulation blocker CTLA-4
H Kahlert et al.
Molecular immunology, 29(10), 1191-1201 (1992-10-01)
Ovalbumin (OVA) is a major allergen (Gal d II) of hen egg white and is often the cause of hypersensitivity reactions to food. Further knowledge of the antigenic and allergenic epitopes of allergens will provide better treatment of this disease.
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