C0399

Cromolyn sodium salt

≥95%

• Synonym(s): Cromoglycate, Cromoglycic acid
• Linear Formula: C₂₃H₁₄O₁₁Na₂
• CAS Number: 15826-37-6
• Molecular Weight: 512.33
• EC Number: 239-926-7
• MDL number: MFCD00057744
• UNSPSC Code: 12352200
• PubChem Substance ID: 24892251
• NACRES: NA.77

Properties

• assay: ≥95%
• form: powder
• originator: Sanofi Aventis
• SMILES string: [Na].OC(COc1cccc2OC(=CC(=O)c12)C(O)=O)COc3cccc4OC(=CC(=O)c34)C(O)=O
• InChI: 1S/C23H16O11.Na.H/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;
• InChI key: UXMUBZWVLQEMRB-UHFFFAOYSA-N

Description

General description

Cromolyn sodium is a mast stabilizer, which is used to treat allergies.[1] It is a bischromone and functions as a non-steroidal anti-inflammatory drug.[2] It inhibits the release of histamines from mast cells.[3]

Application

Cromolyn sodium salt has been used to block mast cell activation and to inhibit histamine secretion from rodent peritoneal mast cells.[4] It has also been used to stabilize mast cells.[5][6]

Biochem/physiol Actions

Cromolyn blocks the release of histamine and other pro-inflammatory mediators from mast cells.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves