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G1639

Sigma-Aldrich

D-(+)-Galactosamine hydrochloride

BioReagent, suitable for cell culture

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Synonym(s):
2-Amino-2-deoxy-D-galactopyranose hydrochloride, D-Chondrosamine hydrochloride
Empirical Formula (Hill Notation):
C6H13NO5 · HCl
CAS Number:
Molecular Weight:
215.63
Beilstein/REAXYS Number:
3697825
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

biological source

fish cartilage (shark)

Quality Level

product line

BioReagent

assay

≥99%

technique(s)

cell culture | mammalian: suitable

impurities

Glucosamine, essentially free

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

Cl.N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO

InChI

1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1

InChI key

CBOJBBMQJBVCMW-NQZVPSPJSA-N

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This Item
G0500G1514A8625
D-(+)-Galactosamine hydrochloride BioReagent, suitable for cell culture

G1639

D-(+)-Galactosamine hydrochloride

D-(+)-Galactosamine hydrochloride ≥99% (HPLC)

G0500

D-(+)-Galactosamine hydrochloride

D-(+)-Glucosamine hydrochloride ≥99%, BioReagent, suitable for cell culture

G1514

D-(+)-Glucosamine hydrochloride

N-Acetyl-D-glucosamine ≥99% (HPLC)

A8625

N-Acetyl-D-glucosamine

biological source

fish cartilage (shark)

biological source

shark (cartilage)

biological source

Aspergillus niger, maize fruit

biological source

crab (red)

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

solubility

H2O: 50 mg/mL, clear to slightly hazy, colorless to very faintly yellow

solubility

water: 100 mg/mL, clear, colorless

solubility

H2O: 50 mg/mL, clear to very slightly hazy (colorless to faint yellow solution)

storage temp.

room temp

storage temp.

room temp

storage temp.

-

storage temp.

−20°C

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

impurities

Glucosamine, essentially free

impurities

≤0.5% Glucosamine (HPAE)

impurities

-

impurities

-

Application

D-(+)-Galactosamine hydrochloride has been used to:
  • induce livery injury
  • inflammatory liver injury
  • acute liver failure (ALF) in mice

Biochem/physiol Actions

Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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