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G5011

Sigma-Aldrich

Glucan from baker's yeast (S. cerevisiae)

≥98.00%

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Synonym(s):
Glucosan
CAS Number:
EC Number:
MDL number:
NACRES:
NA.25

biological source

bakers yeast (S. cerevisiae)

Quality Level

assay

≥98.00%

form

powder

color

white to faint yellow

solubility

water: 9.80-10.20 mg/mL, turbid, colorless to light yellow

storage temp.

2-8°C

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1 of 4

This Item
G6378P7634I1643
biological source

bakers yeast (S. cerevisiae)

biological source

-

biological source

bakers yeast

biological source

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

300

solubility

water: 9.80-10.20 mg/mL, turbid, colorless to light yellow

solubility

-

solubility

-

solubility

-

form

powder

form

lyophilized powder

form

ammonium sulfate suspension

form

powder

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

General description

Glucan is a natural polysaccharide. They are carbohydrates forming structural components, which is found in the cell walls of yeast, fungi, seaweed and cereals.

Application

Glucan from baker′s yeast (S. cerevisiae) has been used:
  • for immune stimulation
  • to stimulate mRNA expression of a sigma class glutathione S-transferase (GST) in hemocytes
  • to study its effects in rainbow trout intestinal epithelial cell line (RTgutGC)

Biochem/physiol Actions

Glucan enhances anti-infectious immunity, prevents cancer growth, lowers stress and reduces cholesterol level. It has immunostimulatory property. It maintains blood sugar level and rejuvenates skin.

Preparation Note

Prepared by the method of Bacon, et al.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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25G
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Customers Also Viewed

Simone J C F M Moorlag et al.
Cell reports, 31(7), 107634-107634 (2020-05-21)
β-glucan is a potent inducer of epigenetic and functional reprogramming of innate immune cells, a process called "trained immunity," resulting in an enhanced host response against secondary infections. We investigate whether β-glucan exposure confers protection against pulmonary Mycobacterium tuberculosis (Mtb)
Jeyachandran Sivakamavalli et al.
Journal of molecular recognition : JMR, 29(5), 186-198 (2015-12-22)
In invertebrates, the prophenoloxidase (proPO) pathway is involved in the phenol-like antioxidant production against invading pathogens. Overproduction of melanin and phenolic substances leads to the disruption of hemocytes (own host cells); therefore, there is a prerequisite to regulate the antioxidant
Glucan supplementation enhances the immune response against an influenza challenge in mice
Vetvicka V and Vetvickova J
Annals of Translational Medicine, 3(2) (2015)
Cheng Man Lun et al.
Immunobiology, 221(8), 889-903 (2016-03-30)
The purple sea urchin, Strongylocentrotus purpuratus, possesses a sophisticated innate immune system that responds to microbes effectively by swift expression of the highly diverse Sp185/333 gene family. The Sp185/333 proteins are predicted to have anti-pathogen functions based on inducible gene
Effects of beta-glucans on the immune system
Akramiene D, et a l.
Medicina, 43(8), 597-597 (2007)

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