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G5889

Sigma-Aldrich

L-Glutamic acid monosodium salt hydrate

BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%

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Synonym(s):
(S)-2-Aminopentanedioic acid, L-Glutamic acid monosodium salt, Glu, MSG, Monosodium glutamate
Empirical Formula (Hill Notation):
C5H8NNaO4 · xH2O
CAS Number:
Molecular Weight:
169.11 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

product line

BioReagent

Quality Level

Assay

≥99%

form

powder

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

color

white to off-white

mp

163 °C

InChI

1S/C5H9NO4.Na.H2O.H/c6-3(5(9)10)1-2-4(7)8;;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2;

InChI key

JYDGDQPVBSBYRT-UHFFFAOYSA-N

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1 of 4

This Item
G162649621G1149
assay

≥99%

assay

≥99% (HPLC)

assay

≥98.0% (NT)

assay

≥99% (HPLC)

form

powder

form

powder

form

solid

form

powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

cell culture | insect: suitable

color

white to off-white

color

white to off-white

color

-

color

white

mp

163 °C

mp

-

mp

232 °C (dec.) (lit.)

mp

-

General description

L-Glutamic acid/monosodium glutamate (MSG) is the sodium salt of glutamic acid. It is a commonly used food additive.

Application

L-Glutamic acid monosodium salt hydrate has been used:
  • to prepare glutamate stock solution in HEPES-buffered saline (HBS) for glutamate perfusions
  • as a component in YNG (yeast nitrogen base glutamate) medium
  • used to treat HT22 hippocampal cells to study its effects on cell viability and to examine the expression of molecules related to apoptotic cell death
  • as a component of fresh media to culture neurons and to assess glutamate uptake

Biochem/physiol Actions

Monosodium glutamate (MSG) is a food additive and an environmental agent, that can affect inflammation.
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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