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About This Item
Linear Formula:
CH3CO2C6H4NO2
CAS Number:
Molecular Weight:
181.15
Beilstein/REAXYS Number:
515874
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
Product Name
4-Nitrophenyl acetate, esterase substrate
Quality Level
assay
≥98% (TLC)
form
powder or crystals
mp
75-77 °C (lit.)
storage temp.
−20°C
SMILES string
CC(=O)Oc1ccc(cc1)[N+]([O-])=O
InChI
1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3
InChI key
QAUUDNIGJSLPSX-UHFFFAOYSA-N
Gene Information
human ... PON1(5444)
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Application
4-Nitrophenyl acetate has been used:
- to evaluate esterase activity in human embryonic kidney cell line
- in carbonic anhydrase inhibition assay
- to study its conversion to p-nitrophenol (p-NP) by the esterase activity of bovine serum albumin
- as a substrate to determine carboxylesterase (CES) activity in mouse liver cells
- to study the advantages of bioconjugation of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) in magnetic CLEAs matrix
Substrates
Chromogenic esterase substrate.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Ox. Sol. 3 - Skin Sens. 1
Storage Class
5.1B - Oxidizing hazardous materials
wgk_germany
WGK 3
flash_point_f
No data available
flash_point_c
No data available
ppe
Eyeshields, Gloves, type N95 (US)
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