MilliporeSigma
All Photos(1)

Documents

N9876

Sigma-Aldrich

4-Nitrophenyl butyrate

≥98%

Sign Into View Organizational & Contract Pricing

Synonym(s):
p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
Empirical Formula (Hill Notation):
C10H11NO4
CAS Number:
Molecular Weight:
209.20
Beilstein/REAXYS Number:
1879729
MDL number:
PubChem Substance ID:
NACRES:
NA.83

Quality Level

assay

≥98%

form

liquid

density

1.19 g/mL at 20 °C (lit.)

storage temp.

−20°C

SMILES string

CCCC(=O)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C10H11NO4/c1-2-3-10(12)15-9-6-4-8(5-7-9)11(13)14/h4-7H,2-3H2,1H3

InChI key

DVDUMIQZEUTAGK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
N4377N8130N2752
4-Nitrophenyl butyrate ≥98%

N9876

4-Nitrophenyl butyrate

4-Nitrophenyl valerate liquid

N4377

4-Nitrophenyl valerate

4-Nitrophenyl acetate esterase substrate

N8130

4-Nitrophenyl acetate

4-Nitrophenyl palmitate lipase substrate

N2752

4-Nitrophenyl palmitate

form

liquid

form

liquid

form

powder or crystals

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

density

1.19 g/mL at 20 °C (lit.)

density

-

density

-

density

-

General description

4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.

Application

4-nitrophenyl butyrate has been used:
  • as a substrate for esterase activity in monocyte-derived macrophage cell line in response to polyethylene
  • as a substrate for mycobacterial phospholipase A and mycobacterial cutinase activity
  • as a substrate to determine the effect of buffers and solvents on human carboxylesterase

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 2

1 of 2

Monitoring lipase/esterase activity by stopped flow in a sequential injection analysis system using p-nitrophenyl butyrate
Pliego J, et al.
Sensors, 15(2), 2798-2811 (2015)
María Molina-Gutiérrez et al.
Food chemistry, 221, 1458-1465 (2016-12-17)
β-sitostanol esters, used as dietary complement for decreasing cholesterol absorption, have been synthesized at 28°C via direct esterification or transesterification catalyzed by the versatile lipase/sterol esterase from the ascomycete fungus O. piceae. Direct esterification was conducted in biphasic isooctane: water
Geum Jin Kim et al.
Antioxidants (Basel, Switzerland), 10(2) (2021-02-10)
Since 2016, the invasive halophyte Spartina anglica has been colonizing mudflats along the western coast of South Korea. In order to minimize costs on S. anglica expansion management and waste-treatment of collected biomass, the potential application of the collected biomass
Differential response to chemically altered polyethylene by activated mature human monocyte-derived macrophages
Xing S, et al.
Biomaterials, 23(17), 3595-3602 (2002)
Sara Arana-Peña et al.
Frontiers in bioengineering and biotechnology, 8, 36-36 (2020-03-18)
The lipase from Pseudomonas fluorescens (PFL) has been immobilized on octyl-agarose beads under 16 different conditions (varying pH, ionic strength, buffer, adding some additives) at two different loadings, 1 and 60 mg of enzyme/g of support with the objective of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service