P5556
Poloxamer 188 solution
10%, sterile-filtered, BioReagent, suitable for insect cell culture
Synonym(s):
Nonionic copolymer surfactant
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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.75
Pricing and availability is not currently available.
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description
non-ionic
sterility
sterile-filtered
product line
BioReagent
mol wt
average mol wt 8350
concentration
10%
technique(s)
cell culture | insect: suitable
impurities
endotoxin, tested
transition temp
cloud point ≥100
HLB
29
SMILES string
O2C(C2)C.O1CC1
General description
Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.[1]
Application
A nonionic copolymer surfactant
Biochem/physiol Actions
Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence.[1][2] P-188 exhibits low toxicity and may be used in oral drug delivery.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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