SAB5700526

Anti-Phospho-Tau-S519/T522 antibody produced in rabbit

• Synonym(s): DDPAC, FTDP-17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, Tau
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 32-45; 78- 80
• species reactivity: mouse, human
• concentration: 0.72 mg/ml
• technique(s): immunofluorescence: 1:50-1:100; western blot: 1:500-1:2000
• UniProt accession no.: P10636
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer519/pThr522)
• Gene Information: human ... MAPT(4137)

Description

General description

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Immunogen

A phospho specific peptide corresponding to residues surrounding S519/T522 of human Tau

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable