MilliporeSigma
All Photos(1)

Documents

T0699

Sigma-Aldrich

Trichloroacetic acid solution

6.1 N

Sign Into View Organizational & Contract Pricing

Synonym(s):
TCA
Linear Formula:
Cl3CCOOH
CAS Number:
Molecular Weight:
163.39
Beilstein/REAXYS Number:
970119
MDL number:
PubChem Substance ID:
NACRES:
NA.26

form

liquid

Quality Level

concentration

6.1 N
~100 % (w/v)

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
T91599123091228
Trichloroacetic acid solution 6.1 N

T0699

Trichloroacetic acid solution

-
Trichloroacetic acid BioXtra, ≥99.0%

T9159

Trichloroacetic acid

Premium Grade
Trichloroacetic acid ACS reagent, for the determination of Fe in blood according to Heilmeyer, ≥99.5%

91230

Trichloroacetic acid

-
Trichloroacetic acid BioUltra, ≥99.5% (T)

91228

Trichloroacetic acid

Premium Grade
Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

liquid

form

-

form

flakes

form

crystals, flakes

General description

Trichloroacetic acid (TCA) is a strong acid. At the pH of drinking water, TCA exists almost in salt form.

Application

Trichloroacetic acid solution has been used:
  • in indoleamine 2,3-dioxygenase (IDO) enzyme assay to hydrolyze N-formylkynurenine and produce kynurenine
  • in the proliferation of human pulmonary artery smooth muscle cells (HPASMCs)
  • to treat ground tissue and precipitate proteins during protein extraction and quantification

Biochem/physiol Actions

Trichloroacetic acid solution is traditionally used to precipitate protein. It can be used to determine protein concentration by quantitative precipitation. Trichloroacetic acid can also be used as a decalcifier and fixative in microscopy.
Trichloroacetic acid (TCA) with no known systemic toxicity, is used as a time-honored agent for superficial peeling. It is a peroxisome proliferator.

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Guillaume Laflamme et al.
Cell reports, 26(11), 2875-2889 (2019-03-14)
The segregation of chromosomes is a critical step during cell division. This process is driven by the elongation of spindle microtubules and is tightly regulated by checkpoint mechanisms. It is unknown whether microtubules affect checkpoint responses as passive contributors or
Hikmat Al-Ahmadie et al.
Cancer discovery, 4(9), 1014-1021 (2014-06-18)
Metastatic solid tumors are almost invariably fatal. Patients with disseminated small-cell cancers have a particularly unfavorable prognosis, with most succumbing to their disease within two years. Here, we report on the genetic and functional analysis of an outlier curative response
Alan Mortensen et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 55-62 (2012-10-17)
The ratio of the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (BH(4)) to its oxidized form dihydrobiopterin (BH(2)) has been suggested as an index of endothelial dysfunction. Consequently, much effort has been put into preserving the in vivo equilibrium between these
Ying Wang et al.
Diabetes, 63(8), 2643-2655 (2014-03-13)
After diabetes, the heart has a singular reliance on fatty acid (FA) for energy production, which is achieved by increased coronary lipoprotein lipase (LPL) that breaks down circulating triglycerides. Coronary LPL originates from cardiomyocytes, and to translocate to the vascular
Verena Pfahler et al.
The New phytologist, 197(1), 186-193 (2012-10-31)
The objective of this study was to investigate the isotopic composition of oxygen bound to phosphate (δ(18)O-PO(4)) in different phosphorus (P) pools in plant leaves. As a model plant we used soybean (Glycine max cv Toliman) grown in the presence

Protocols

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

This procedure may be used for determination of Pepsin activity using hemoglobin as the substrate. It is a spectrophotometric stop rate determination.

This procedure may be used for the determination of Amyloglucosidase activity using starch as the substrate.

Proteinase K activity measured via spectrophotometry using hemoglobin substrate, crucial for enzyme characterization.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service