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T0895

Sigma-Aldrich

Thymine

BioReagent, suitable for cell culture

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Synonym(s):
2,4-Dihydroxy-5-methylpyrimidine, 5-Methyluracil
Empirical Formula (Hill Notation):
C5H6N2O2
CAS Number:
Molecular Weight:
126.11
Beilstein/REAXYS Number:
117880
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

biological source

synthetic

Quality Level

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

~320 °C (dec.) (lit.)

solubility

1 M NaOH: 50 mg/mL, clear to hazy, colorless to faintly yellow

SMILES string

CC1=CNC(=O)NC1=O

InChI

1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

InChI key

RWQNBRDOKXIBIV-UHFFFAOYSA-N

Gene Information

mouse ... Tymp(72962)

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This Item
T0376T37631724532
vibrant-m

T0895

Thymine

vibrant-m

T0376

Thymine

vibrant-m

T3763

α-Thymidine

vibrant-m

1724532

Zidovudine Related Compound C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

form

powder

form

powder

form

powder

form

-

assay

≥99% (HPLC)

assay

≥99%

assay

≥98% (HPLC)

assay

-

solubility

1 M NaOH: 50 mg/mL, clear to hazy, colorless to faintly yellow

solubility

-

solubility

water: 50 mg/mL, clear, colorless

solubility

-

mp

~320 °C (dec.) (lit.)

mp

~320 °C (dec.) (lit.)

mp

-

mp

~320 °C (dec.) (lit.)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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25G
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705578-5MG-PW

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MMYOMAG-74K-13

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Subhendu Sekhar Bag et al.
The Journal of organic chemistry, 78(2), 278-291 (2012-11-23)
We report the design and synthesis of triazolyl donor/acceptor unnatural nucleosides via click chemistry and studies on the duplex stabilization of DNA containing two such new nucleosides. The observed duplex stabilization among the self-pair/heteropair has been found to be comparable
Stefano Stella et al.
Acta crystallographica. Section D, Biological crystallography, 69(Pt 9), 1707-1716 (2013-09-04)
Transcription activator-like effectors contain a DNA-binding domain organized in tandem repeats. The repeats include two adjacent residues known as the repeat variable di-residue, which recognize a single base pair, establishing a direct code between the dipeptides and the target DNA.
M Weinfeld et al.
Progress in nucleic acid research and molecular biology, 68, 139-149 (2001-09-14)
The toxic and mutagenic effects of ionizing radiation are believed to be caused by damage to cellular DNA. We have made use of a novel immunoassay for thymine glycol to examine the removal of this lesion from the DNA of
S I Ahmad et al.
Annual review of microbiology, 52, 591-625 (1999-01-19)
For many years it has been known that thymine auxotrophic microorganisms undergo cell death in response to thymine starvation [thymineless death (TLD)]. This effect is unusual in that deprivation of many other nutritional requirements has a biostatic, but not lethal
Javier A Tello et al.
American journal of physiology. Endocrinology and metabolism, 305(1), E67-E77 (2013-05-02)
The human GnRH receptor (GNRHR1) has a specific set of properties with physiological and pharmacological influences not appropriately modeled in laboratory animals or cell-based systems. To address this deficiency, we have generated human GNRHR1 knock-in mice and described their reproductive

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