T6140

N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt

plasmin substrate, chromogenic, ≥98% (TLC), powder

• Synonym(s): N-Tosylglycyl-L-prolyl-L-lysine 4-nitroanilide acetate salt
• Linear Formula: C₂₆H₃₄N₆O₇S · C₂H₄O₂
• CAS Number: 88793-79-7
• Molecular Weight: 634.70
• EC Number: 289-446-7
• MDL number: MFCD00057232
• UNSPSC Code: 12352204
• PubChem Substance ID: 24900352
• NACRES: NA.32

Properties

• product name: N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt, plasmin substrate
• assay: ≥98% (TLC)
• form: powder
• solubility: ethanol: 50 mg/mL, colorless to yellow
• storage temp.: −20°C
• SMILES string: CC(O)=O.Cc1ccc(cc1)S(=O)(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)Nc3ccc(cc3)[N+]([O-])=O
• InChI: 1S/C26H34N6O7S.C2H4O2/c1-18-7-13-21(14-8-18)40(38,39)28-17-24(33)31-16-4-6-23(31)26(35)30-22(5-2-3-15-27)25(34)29-19-9-11-20(12-10-19)32(36)37;1-2(3)4/h7-14,22-23,28H,2-6,15-17,27H2,1H3,(H,29,34)(H,30,35);1H3,(H,3,4)/t22-,23-;/m0./s1
• InChI key: KPGSNEYSJPIZCW-SJEIDVEUSA-N

Description

Application

N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt has been used:

• as a substrate for examining the amidolytic activity of aprE2, aprE5-41
• as a substrate for serine protease and fibrinogenolytic assays
• as a substrate for plasmin assay

Biochem/physiol Actions

N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt is a chromogenic substrate for plasmin assay, serine protease enzyme activity and fibrinogenolytic assays.

Substrates

A chromogenic substrate for plasmin.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)