Bioprocessing Cell Culture Media & Feeds
For decades, biopharmaceutical companies have relied on our high-performing cell culture media (CCM) to intensify their processes and optimize production. Whether you are improving your cell culture process, perfecting your vaccine production, advancing your cell and gene therapy process, or pursuing tailored solutions meeting your specific cell culture process needs, our CCM and feeds empower you to achieve robust and efficient results.
What makes our media unique?
- Extensive Portfolio: Explore our comprehensive range of media and feeds, featuring both established and innovative formulations for process intensification of monoclonal antibodies and novel modalities such as cell and gene therapies.
- Unrivaled Quality and Performance: Enhance cell culture productivity with our chemically defined, animal origin-free media and feeds. Designed to streamline upstream workflows across all applications, our rigorously tested products ensure improved safety, regulatory compliance, and consistent performance.
- Tailored Solutions: Rely on our global manufacturing network for customized dry powder and liquid media, designed to meet your unique requirements at any scale and for any application, ensuring a perfect match.
- Expert Technical Support: Get top-tier application support from a dedicated team with expertise in various cell types, biologics, metabolic needs, and process requirements. We are fully committed to meeting your business continuity and process needs.
- Risk Mitigation Support: Leverage our Emprove® CCM documentation to gain full transparency and comprehensive information needed for your qualification, risk assessment, and process optimization efforts
Section Overview
In CHO cell culture, process intensification, media consistency and easy handling are critical. Our chemically defined formulations for cell line development, seed train, fed-batch, and perfusion are meticulously designed to support cell vitality and maximize productivity of CHO-based applications. We leverage innovative solutions such as modified amino acids, a novel poloxamer, low-impurity iron, and compacted CCM to align with novel process designs and facilitate upstream process intensification. In fed-batch processes, our highly concentrated one-part pH-neutral feeds support a streamlined workflow, replenishing depleted nutrients and reducing feed volume, ultimately increasing product yield.
Explore our Cellvento® ModiFeed platform supporting your individual feeding strategy:
Insect Cell Media for Vaccine and Gene Therapy Production
The production of recombinant proteins, virus-like particles, and adeno-associated viruses (AAV) for vaccines and gene therapy with insect cells demands specialized media that deliver outstanding performance and quality. Our chemically defined media is tailored to support robust growth of multiple insect cell lines, such as Sf-RVN®, Sf-9, Sf-21, S2, Tni and C636.
Explore our key products for excellent productivity and high-quality titers in insect cell culture:
HEK293 Media for Production of Gene Therapy
The human cell line HEK293 is widely used in the production of viral vectors for gene therapy and gene-modified cell therapy. Our chemically defined, animal-component-free HEK293 media is specifically formulated for optimal cell expansion, transient transfection, and high titers in AAV and lentivirus production, supporting suspension cell culture and a broad range of transfection agents, including cationic polymers such as PEI.
Discover our key products for excellent growth and productivity of HEK cell lines:
Custom Cell Culture Solutions
Individual applications require dedicated solutions. Whether you require dry powder or liquid formulations, for pre-GMP or GMP applications, small- or large-scale production, our global network of technical experts and manufacturing sites is committed to providing you with a solution tailored to your needs.
Find more information on our custom offering here:
Related Product Resources
- Guide: CHO Cell Culture Media and Feeds
Discover Cellvento® and EX-CELL® CHO cell culture media and feeds, a comprehensive range of off-the-shelf products to support all your CHO production processes and cell line development needs.
- White Paper: Improving Fed-batch Yields by Combining EX-CELL® Advanced and Cellvento® Cell Culture Media Portfolios
Unveil the keys to skyrocketing fed-batch yields in bioprocessing by uncovering a plethora of strategies and techniques to optimize your production and achieve exceptional results.
- White Paper: Accelerating Cell Line and Process Development
Immerse yourself in the captivating world of CHOZN® UCOE (Ubiquitous Chromatin Opening Elements) technology, offering exceptional benefits and versatile applications to maximize biopharmaceutical production in mammalian cell line development.
- White Paper: Strategies for Upstream Intensification
Discover a world of groundbreaking strategies and insightful perspectives for upstream intensification in bioprocessing, empowering you to enhance productivity and achieve unparalleled results.
- White Paper: Optimizing Media Feeding Strategies Guidance for Cellvento® CHO Media Platform (1st Gen)
Unleash the boundless potential of Cellvento™ CHO media, harnessing its extraordinary capabilities and advantages to foster vigorous cell growth and optimize bioproduction efficiency like never before.
- White Paper: Use of a Chemically Defined Cloning Medium for Quality and Regulatory Risk Mitigation in Cell Line Development
Embark on a journey of discovery with chemically defined cloning medium, unveiling its tremendous potential in boosting cloning efficiency and streamlining molecular biology workflows to deliver unparalleled results.
Related Videos
Related Webinars
In this webinar, you will learn common challenges faced in upstream development, benefits of a one-step & neutral pH feed optimization strategy, potential application of chemically defined hydrolysates, and benefits of supplement targeted at adjusting glycosylation attributes.
In this webinar, you will learn how combining media specifically designed for seed train, production and harvest intensification, can increase the cell specific productivity (Qp) in the final production stage.
In this webinar, you will learn different variations of perfused seed train, potential benefits from high seed fed batch vs. traditional fed batch, impact of perfused seed trains in single bioreactor vs. multiple bioreactor scenarios, and impact of perfused seed trains in multiple production/seed train ratio scenarios.
Explore the possibilities of using Raman spectroscopy for quality control of cell culture media preparation.
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