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Identification of transformation products of pesticides and veterinary drugs in food and related matrices: use of retrospective analysis.

Identification of transformation products of pesticides and veterinary drugs in food and related matrices: use of retrospective analysis.

Journal of chromatography. A (2015-03-10)

María Luz Gómez-Pérez, Roberto Romero-González, José Luis Martínez Vidal, Antonia Garrido Frenich

ABSTRACT

Retrospective analysis has been applied in different samples, including honey, meat, feed and nutraceutical products from ginkgo biloba, soya, royal jelly and green tea, with the aim of searching transformation products of pesticides and veterinary drugs, which were not included in an initial analysis. Generic extraction and analytical procedures based on high resolution mass spectrometry (Exactive-Orbitrap analyser was used) have been applied. All obtained data have been reprocessed and some compounds as anhydroerythromycin in honey and 3,5,6-trichloro-2-pyridinol in feed have been detected, demonstrating the applicability and the utility of the procedure. Advantages and disadvantages of retrospective approach have been highlighted.

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

Sodium dodecyl sulfate, ≥99.0% (GC), dust-free pellets

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Acetone, SAJ first grade, ≥99.0%

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Sodium dodecyl sulfate, SAJ special grade, ≥97.0%

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Sodium dodecyl sulfate, ≥99.0%

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Acetic acid, 99.5-100.0%

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Methanol, SAJ first grade, ≥99.5%

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Acetone, ≥99.5%, for residue analysis

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Acetic acid, SAJ first grade, ≥99.0%

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Methanol, JIS 300, ≥99.8%, for residue analysis

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Acetic acid, JIS special grade, ≥99.7%

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Acetic acid solution, 1 M, 1 N

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Acetic acid, ≥99.7%

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Acetic acid, ≥99.7%

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Acetone, for residue analysis, ≥99.5%

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Methanol, SAJ special grade

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Acetone, for residue analysis, JIS 5000

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Acetone, suitable for HPLC

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Acetone, JIS special grade, ≥99.5%

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Acetonitrile solution, contains 0.05 % (w/v) ammonium formate, 5 % (v/v) water, 0.1 % (v/v) formic acid, suitable for HPLC

Supelco

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Sodium dodecyl sulfate, suitable for ion pair chromatography, LiChropur^™, ≥99.0%

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