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MilliporeSigma

Viral Clearance

A blue and silver industrial device for large-scale virus filtration with a digital display

Viral safety is a critical aspect of biologics production and relies on the principles of "prevent, detect and remove" to assure viral safety of drugs for patients. Preventing contamination of upstream cell culture processes relies on sourcing and testing raw materials and different technologies to remove viral contaminants. Downstream purification includes steps that either remove or inactivate viruses to provide the clearance required to assure viral safety. 

Our viral clearance portfolio includes the virus filtration solutions, chemicals, holders and systems you need to assure reliable viral safety for your production process. 



Graphic of Virus Inactivation: A: Heat Inactivation; B: Low pH Treatment; C: Detergent Treatment

Virus Inactivation

Enhance biopharma safety and compliance with our virus inactivation solutions, including pasteurization and low pH treatment.

Integrity Testers

Efficient Filter Integrity Testing: Elevate quality control with Integritest® 5, offering bubble point, diffusion, and hydrophobic testing in-line or offline.

Integritest® 5 integrity tester

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Viresolve® Barrier capsules and Viresolve® Pro Devices used to assure viral safety in cell culture media and downstream processing
Virus Filters

Viral safety is a key component of drug safety for patients. Learn how virus filtration reduces risk, assures viral clearance, and enhances viral safety.

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The Mobius® FlexReady solution for large-scale virus filtration
Virus Filter Holders and Systems

Flexible, easy-to-use filter holders are a key component for integration of the Viresolve® Pro Solution, enabling scalable virus filtration that meets your manufacturing demands.

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