254606

(−)-メチル (S)-2,2-ジメチル-1,3-ジオキソラン-4-カルボキシラート

96%

• 別名: α,β-イソプロピリデン-L-グリセリン酸メチル, α,β-イソプロピリデン-L-グリセリン酸メチルエステル, 2,3-O-イソプロピリデン-L-グリセリン酸メチル
• 実験式（ヒル表記法）: C₇H₁₂O₄
• CAS番号: 60456-21-5
• 分子量: 160.17
• Beilstein: 4292352
• MDL番号: MFCD00066526
• UNSPSCコード: 12352005
• PubChem Substance ID: 24855396
• NACRES: NA.22

特性

• 品質水準: 200
• アッセイ: 96%
• 形状: liquid
• 光学活性: [α]20/D −8.5°, c = 1.5 in acetone
• 光学純度: ee: ≥96.0% (GLC)
• 屈折率: n20/D 1.425 (lit.)
• bp: 84-86 °C/15 mmHg (lit.)
• 密度: 1.106 g/mL at 25 °C (lit.)
• 官能基: ester; ether; ketal
• SMILES記法: COC(=O)[C@@H]1COC(C)(C)O1
• InChI: 1S/C7H12O4/c1-7(2)10-4-5(11-7)6(8)9-3/h5H,4H2,1-3H3/t5-/m0/s1
• InChI Key: DOWWCCDWPKGNGX-YFKPBYRVSA-N

詳細

アプリケーション

(−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate can be used:

• As a chiral building block to make the key tetrahydrofuran subunit of (−)-gymnodimine, a marine algal toxin.
• To prepare an enedione by reacting with dimethyl methylphosphonate, BuLi, and phenylglyoxal, which in turn is used to synthesize cyclopentenone derivatives.
• As a starting material for the preparation of (S)-4,5-dihydroxy-2,3-pentanedione (DPD), a precursor for autoinducer (AI)-2 in bacteria.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): 172.4 °F - closed cup
• 引火点(℃): 78 °C - closed cup
• 個人用保護具 (PPE): Eyeshields, Gloves, type ABEK (EN14387) respirator filter