27370

シンコニン

crystallized, ≥98.0% (NT)

• 別名: NSC 6176
• 実験式（ヒル表記法）: C₁₉H₂₂N₂O
• CAS番号: 118-10-5
• 分子量: 294.39
• Beilstein: 89689
• EC Number: 204-234-6
• MDL番号: MFCD00064372
• UNSPSCコード: 12352104
• PubChem Substance ID: 57648242
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: ≥98.0% (NT)
• フォーム: powder
• 光学活性: [α]20/D +225±5°, c = 0.5% in ethanol
• 品質: crystallized
• 不純物: ~15% dihydrocinchonine (HPLC)
• mp: 260-263 °C
• 官能基: hydroxyl
• SMILES記法: O[C@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34
• InChI: 1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18+,19-/m0/s1
• InChI Key: KMPWYEUPVWOPIM-QAMTZSDWSA-N
• 遺伝子情報: human ... CYP2D6(1565)

詳細

詳細

Cinchonine is a cinchona alkaloid generally found in the bark of Cinchona officinalis plants. It is a pseudoenantiomer that is commonly employed in malaria therapy. Cinchonine is also used as an organocatalyst in many asymmetric reactions.

アプリケーション

Cinchonine can be used:

• As a substrate in the study of supercritical fluid chromatography (SFC) parameters in pharmaceutical analysis.
• To prepare possible butyrylcholinesterase inhibitors.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H317
• 注意書き: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• 危険有害性の分類: Acute Tox. 4 Oral - Skin Sens. 1A
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves