298891

(4R,5S)-(+)-4-メチル-5-フェニル-2-オキサゾリジノン

99%

• 別名: (4R,5S)-4-メチル-5-フェニル-2-オキサゾリジノン
• 実験式（ヒル表記法）: C₁₀H₁₁NO₂
• CAS番号: 77943-39-6
• 分子量: 177.20
• Beilstein: 1211705
• MDL番号: MFCD00010845
• UNSPSCコード: 12352005
• PubChem Substance ID: 24858003
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 99%
• フォーム: solid
• 光学活性: [α]18/D +168°, c = 2 in chloroform
• 光学純度: ee: 98% (GLC)
• mp: 121-123 °C (lit.)
• SMILES記法: C[C@H]1NC(=O)O[C@H]1c2ccccc2
• InChI: 1S/C10H11NO2/c1-7-9(13-10(12)11-7)8-5-3-2-4-6-8/h2-7,9H,1H3,(H,11,12)/t7-,9-/m1/s1
• InChI Key: PPIBJOQGAJBQDF-VXNVDRBHSA-N

詳細

アプリケーション

Evan′s chiral auxiliary (4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone reacts with carboxylic acids to produce corresponding acyl derivatives in the presence of a diisopropylcarbodiimide reagent. It can also employed in the preparation of N-sulfinyloxazolidinone reagent (chiral sulfinyl transfer reagent), which reacts with nucleophiles such as Grignard reagents, enolates, and metalated amides to produce the chiral sulfoxides, sulfinate esters, and sulfonamides.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)