349666

2-Phenylbutyryl chloride

98%

• 化学式: C₂H₅CH(C₆H₅)COCl
• CAS番号: 36854-57-6
• 分子量: 182.65
• EC Number: 253-241-0
• MDL番号: MFCD00018811
• UNSPSCコード: 12352100
• PubChem Substance ID: 24861697
• NACRES: NA.22
• フォーム: liquid
• アッセイ: 98%

特性

• 品質水準: 100
• アッセイ: 98%
• フォーム: liquid
• 屈折率: n20/D 1.516 (lit.)
• bp: 122-125 °C/20 mmHg (lit.)
• 密度: 1.093 g/mL at 25 °C (lit.)
• 官能基: acyl chloride; phenyl
• SMILES記法: CCC(C(Cl)=O)c1ccccc1
• InChI: 1S/C10H11ClO/c1-2-9(10(11)12)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3
• InChI Key: QGXMHCMPIAYMGT-UHFFFAOYSA-N

詳細

詳細

The kinetic resolution of racemic 2-phenylbutyryl chloride by sterically hindered chiral secondary alcohols has been evaluated. 2-Phenylbutyryl chloride reacts with 4-methoxybenzoyl chloride catalyzed by PdBr(Ph)(PPh₃)₂ to yield 1-(4-methoxyphenyl)-2-phenyl-2-buten-1-one.

アプリケーション

(R)-(-)-2-phenylbutyryl chloride may be employed as chiral reagent for the determination of dopamine and dopamine-derived salsolinol and norsalsolinol in human brain by GC-MS method. Chiral (S)-(+)-2-phenylbutyryl chloride may be used as derivatization reagent for the hydroxyl groups during the GC-MS assay for the enantiomers of 1,2-propanediol, 1,3-butanediol, 1,3-pentanediol and their corresponding hydroxyacids in biological fluids.

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Danger
• 危険有害性情報: H314
• 注意書き: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• 危険有害性の分類: Skin Corr. 1B
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• 引火点(°F): 208.4 °F - closed cup
• 引火点(℃): 98 °C - closed cup
• 個人用保護具 (PPE): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter