763896

DL-α-トコフェロールメトキシポリエチレングリコールスクシナート

• 別名: Polyethylene glycol, TPGS-750-M
• CAS番号: 1309573-60-1
• UNSPSCコード: 51171641
• NACRES: NA.22

特性

• 形状: powder
• 品質水準: 100
• 反応適合性: reagent type: catalyst; reaction type: C-H Activation; reagent type: surfactant
• 環境により配慮した代替製品の特徴: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• 転移温度: T_m 29-34
• 環境により配慮した代替製品カテゴリ: , Aligned

詳細

詳細

Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.

アプリケーション

On the Way Towards Greener Transition-Metal-Catalyzed Processes as Quantified by E Factors

DL-α-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M), a biodegradable and water-soluble derivative of natural vitamin E, is used as an environmentally benign nonionic surfactant in metal-catalyzed cross-coupling reactions in water. It is used in Heck, Suzuki-Miyaura, Sonogashira, and Negishi like couplings reactions. It can also be utilized in aminations, C-H activations, and olefin metathesis reactions.
TPGS-750-M can also be employed in:

• The nucleophilic aromatic substitution reaction of aryl and heteroaryl halides with nitrogen, oxygen, and sulfur nucleophiles under mild conditions.
• The preparation of quinoxaline-2,3 diones from quinoxalinones via C(sp²)-H hydroxylation reaction.
• The intramolecular N-arylation of amines using a copper catalyst.

その他情報

Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable