QBD10502

Azido-dPEG^®₄-acid

• 別名: 15-Azido-4,7,10,13-tetraoxapentadecanoic acid, 3-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid, Polyethylene glycol
• 実験式（ヒル表記法）: C₁₁H₂₁N₃O₆
• CAS番号: 1257063-35-6
• 分子量: 291.30
• MDL番号: MFCD12406155
• UNSPSCコード: 12352106
• PubChem Substance ID: 329823931
• NACRES: NA.22

特性

• アッセイ: >90%
• 形状: solid or viscous liquid
• 反応適合性: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• 官能基: azide; carboxylic acid
• ポリマー構造: shape: linear; functionality: heterobifunctional
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: OC(CCOCCOCCOCCOCCN=[N+]=[N-])=O
• InChI: 1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16)
• InChI Key: BODPHGOBXPGJKO-UHFFFAOYSA-N

詳細

特徴および利点

The azido-dPEG^®₄ contains an azide function on one end of a single molecular weight dPEG^® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The acid function may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法的情報

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable