コンテンツへスキップ
Merck
すべての画像(1)

主要文書

04-290

Sigma-Aldrich

Anti-EGFR (CT) Antibody, clone 13G8

clone 13G8, from mouse

別名:

ERBB, mENA, ERBB1

ログイン組織・契約価格を表示する


About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41
クローン:
13G8, monoclonal
application:
ELISA
ICC
WB
化学種の反応性:
mouse, human
テクニック:
ELISA: suitable
immunocytochemistry: suitable
western blot: suitable
citations:
8

由来生物

mouse

品質水準

抗体製品の状態

purified antibody

抗体製品タイプ

primary antibodies

クローン

13G8, monoclonal

化学種の反応性

mouse, human

メーカー/製品名

Chemicon®
Upstate®

テクニック

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

アイソタイプ

IgG1

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... EGFR(1956)
mouse ... Egfr(13649)

特異性

Recognizes C-terminus domain of EGF receptor (aa1165-1186)

免疫原

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of the C terminus in human EGFR

アプリケーション

Research Category
細胞シグナル伝達
Research Sub Category
成長因子及び受容体
Anti-EGFR (C-terminus) Antibody, clone 13G8 detects level of EGFR (C-terminus) & has been published & validated for use in ELISA, IC & WB.

品質

Routinely evaluated by immunoblot.

ターゲットの説明

180 kDa

関連事項

Replaces: 04-337; 04-338

物理的形状

Subsequent thiophilic adsorption and size exclusion chromatography
100 µg of purified mouse monoclonal IgG lyophilized in PBS containing 0.09% sodium azide, PEG, and sucrose
Format: Purified

保管および安定性

2 years at -20°C from date of shipment

アナリシスノート

Control
Includes EGF treated Hep2G lysate as a positive control

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

適切な製品が見つかりませんか。  

製品選択ツール.をお試しください

保管分類コード

10 - Combustible liquids


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Xiaozhu Zhang et al.
Journal of medical genetics, 44(3), 166-172 (2006-12-13)
Frequent overexpression of epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) makes EGFR a new therapeutic target. Two specific EGFR tyrosine kinase inhibitors, gefitinib (ZD1839, Iressa) and erlotinib (OSI-774, Tarceva), have been developed and approved by the US
Katsuyuki Hotta et al.
Oncology reports, 17(2), 313-317 (2007-01-05)
Despite its tremendous antitumor effect in a subset of patients with non-small cell lung cancer (NSCLC), the exact mechanism of gefitinib-induced cell death has not been fully determined. In this study, forms of cell death in various NSCLC cell lines
Francesca Walker et al.
Experimental cell research, 313(3), 511-526 (2006-12-13)
The site of action of growth factors on mammalian cell cycle has been assigned to the boundary between the G1 and S phases. We show here that Epidermal Growth Factor (EGF) is also required for mitosis. BaF/3 cells expressing the
David W M Tan et al.
Development (Cambridge, England), 140(7), 1433-1444 (2013-03-14)
Human epidermal stem cells express high levels of β1 integrins, delta-like 1 (DLL1) and the EGFR antagonist LRIG1. However, there is cell-to-cell variation in the relative abundance of DLL1 and LRIG1 mRNA transcripts. Single-cell global gene expression profiling showed that
Gayan I Balasooriya et al.
Developmental cell, 37(1), 85-97 (2016-04-06)
The steady-state airway epithelium has a low rate of stem cell turnover but can nevertheless mount a rapid proliferative response following injury. This suggests a mechanism to restrain proliferation at steady state. One such mechanism has been identified in skeletal

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

製品に関するお問い合わせはこちら(テクニカルサービス)