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無菌性
non-sterile
品質水準
フォーム
solid
比活性
≥25 IU/mg (dry basis)
メーカー／製品名
Calbiochem®
保管条件
OK to freeze
不純物
<10 EU/mg Endotoxin (EU/mg protein)
色
white to off-white
溶解性
0.01 M HCl: soluble
輸送温度
wet ice
保管温度
−20°C
InChI Key
PBGKTOXHQIOBKM-FHFVDXKLSA-N
詳細
Recombinant, human insulin (zinc) expressed in P. pastoris. A peptide anabolic hormone produced by pancreatic β-cells.
Recombinant, human insulin (zinc) expressed in P. pastoris. Peptide anabolic hormone produced by pancreatic β-cells. Increases the synthesis of protein, fat, glycogen, and substrate oxidation in mitochondria. Interacts with membrane insulin receptor to cause its biological actions.
警告
Toxicity: Standard Handling (A)
調製ノート
Insulin is practically insoluble from pH 4.5-7.0.
再構成
Following reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 6 weeks at 4°C.
その他情報
Mohan, C., et al. 1989. Curr. Topics Cell. Reg.30, 105.
Johnson, I.S. 1983. Science219, 632.
Johnson, I.S. 1983. Science219, 632.
法的情報
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類コード
11 - Combustible Solids
WGK
nwg
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
US2407709-50:
407709-MG:
407709-1GM:
407709-0GM:
407709-50MG:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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Mohan Sreelekshmi et al.
Journal of biochemical and molecular toxicology, 35(6), 1-8 (2021-03-03)
Glucokinase (GK), a key regulator of hepatic glucose metabolism in the liver and glucose sensor and mediator in the secretion of insulin in the pancreas, is not studied in detail for its therapeutic application in diabetes. Herein, we study the
Medha Sharma et al.
Cell communication and signaling : CCS, 20(1), 179-179 (2022-11-16)
The aim of the present study was to determine the role of individual PHLPP isoforms in insulin signaling and insulin resistance in neuronal cells. PHLPP isoforms were either silenced or overexpressed individually, and the effects were observed on individual Akt
Yamini Yadav et al.
The FEBS journal, 289(23), 7561-7581 (2022-07-11)
PP2Cα is one of the newly identified isoforms of metal-dependent protein phosphatases (PPM). The role of this phosphatase in neuronal insulin signalling is completely unknown. In the present study, we show insulin-mediated rapid upregulation of a protein of the insulin
Kapil Manglani et al.
Cell biology international, 46(3), 488-497 (2021-12-06)
Role of CDK5 and its inhibition in various neuronal processes and functions are well established. However, role of CDK5 and its inhibition in neuronal insulin-signaling and-resistance is not yet explored. In the present study, we investigated the effect of CDK5
Kerrie A Morrison et al.
Scientific reports, 12(1), 3532-3532 (2022-03-05)
Extraction of integral membrane proteins with poly(styrene-co-maleic acid) provides a promising alternative to detergent extraction. A major advantage of extraction using copolymers rather than detergent is the retention of the lipid bilayer around the proteins. Here we report the first
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