580553

(±)-タキシホリン 水和物

An antioxidant flavonoid that scavenges superoxide (1.5 x 10⁵ M⁻¹ s⁻¹) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.

• 別名: 3,3′,4′,5,7-ペンタヒドロキシフラバノン 水和物, ジヒドロケルセチン 水和物
• 実験式（ヒル表記法）: C₁₅H₁₂O₇ · xH₂O
• CAS番号: 24198-97-8
• 分子量: 304.25 (anhydrous basis)
• MDL番号: MFCD11044454
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: white to off-white
• 溶解性: ethanol: 20 mg/mL
• 輸送温度: ambient
• 保管温度: 2-8°C
• SMILES記法: O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3
• InChI: 1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1
• InChI Key: DNQPGSVMBPSRIR-LDXVYITESA-N

詳細

詳細

An antioxidant flavonoid that scavenges superoxide (1.5 x 10⁵ M^-1 s^-1) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.

An antioxidant flavonoid that suppresses the cytotoxicity of superoxide ions and hydrogen peroxide in Chinese hamster V79 cells.

生物化学的／生理学的作用

Cell permeable: no

Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

Primary Target
An antioxidant flavonoid that scavenges superoxide

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Harmful (C)

その他情報

Kostyuk, V.A., et al. 1998. Arch. Biochem. Biophys. 355, 43.
Bors, W., et al. 1995. Free Radic. Biol. Med. 19, 45.
Nakayama, T., et al. 1994. Cancer Res. 54, 1991s.
Nakayama, T., et al. 1993. Biochem. Pharmacol. 45, 265.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable