T4512

(±)-タキシホリン 水和物

≥90% (HPLC)

• 別名: 3,3′,4′,5,7-ペンタヒドロキシフラバノン 水和物, ジヒドロケルセチン 水和物
• 実験式（ヒル表記法）: C₁₅H₁₂O₇ · xH₂O
• CAS番号: 24198-97-8
• 分子量: 304.25 (anhydrous basis)
• MDL番号: MFCD11044454
• UNSPSCコード: 12352200
• PubChem Substance ID: 24278739
• NACRES: NA.25

特性

• 品質水準: 100
• アッセイ: ≥90% (HPLC)
• 形状: powder
• 溶解性: DMSO: 20 mg/mL
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• 保管温度: −20°C
• SMILES記法: O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3
• InChI: 1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1
• InChI Key: DNQPGSVMBPSRIR-LDXVYITESA-N
• 遺伝子情報: mouse ... Hexa(15211)

詳細

詳細

Taxifolin or dihydroquercetin is a naturally occurring secondary metabolic compound found in many plants such as onions, milk thistle, Douglas fir bark, and French maritime pine bark.

アプリケーション

(±)-Taxifolin hydrate has been used to evaluate its effects when co-supplemented with trehalose to improve the quality of post-thawed ram semen. It may have been used as a reference standard to analyze the bioactive components of ethanolic extract of P. orientale (POE) using high-performance liquid chromatography (HPLC).

生物化学的／生理学的作用

(±)-Taxifolin exerts various pharmacological properties that include anti-inflammatory, anti-cancer, antiviral, and antimicrobial activities. It displays neuroprotective, hepatoprotective effects, and it also protects against cardiovascular diseases.

Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves