581500

TEMPOL

≥95% (HPLC), crystals,powder, free radical scavenger and nitric oxide spin trap, Calbiochem^®

• 別名: TEMPOL, 4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
• 実験式（ヒル表記法）: C₉H₁₈NO₂
• CAS番号: 2226-96-2
• 分子量: 172.24
• MDL番号: MFCD00006478
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• product name: TEMPOL, A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap.
• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: crystals; powder
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: orange
• 溶解性: DMSO: 5 mg/mL; ethanol: soluble; water: soluble
• 輸送温度: ambient
• 保管温度: −20°C
• InChI: 1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3
• InChI Key: UZFMOKQJFYMBGY-UHFFFAOYSA-N

詳細

詳細

A stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21^WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21^WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.

生物化学的／生理学的作用

Cell permeable: yes

Primary Target
Free radical scavenger and nitric oxide spin trap

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Harmful (C)

再構成

Prepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).

その他情報

Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med.29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo)41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS08,GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H318,H373
• 注意書き: P260 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P314
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2 Oral
• ターゲットの組織: Liver,spleen
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): 294.8 °F - DIN 51758
• 引火点(℃): 146 °C - DIN 51758