8.18043

Trifluoromethanesulfonic anhydride

for synthesis

• 別名: Trifluoromethanesulfonic anhydride
• 化学式: (CF₃SO₂)₂O
• CAS番号: 358-23-6
• 分子量: 282.14
• MDL番号: MFCD00000408
• UNSPSCコード: 12352106
• EC Index Number: 206-616-8
• NACRES: NA.22

特性

• 品質水準: 200
• アッセイ: ≥99.0% (acidimetric)
• 形状: liquid
• 有効性: 1012 mg/kg LD₅₀, oral (Rat)
• 密度: 1.71 g/cm³ at 20 °C
• 保管温度: 2-30°C
• InChI: 1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8
• InChI Key: WJKHJLXJJJATHN-UHFFFAOYSA-N

詳細

アプリケーション

• Electrophilic activation using trifluoromethanesulfonic anhydride: This method is utilized for transformations of amides, sulfoxides, and phosphorus oxides through nucleophilic trapping, highlighting its versatility in organic synthesis (Huang and Kang, 2022).
• Triflic anhydride in organic synthesis: A comprehensive review of triflic anhydride′s roles, focusing on its application across various organic transformations (Qin, Cheng, and Jiao, 2023).
• Synthesis of nitriles: Employing trifluoromethanesulfonic anhydride for converting aldoximes to nitriles under mild conditions, showcasing an innovative application in nitrile synthesis (Uludag, 2020).
• Hydrotrifluoromethylthiolation of alkenes: Uses trifluoromethanesulfonic anhydride for the hydrotrifluoromethylthiolation of unactivated alkenes and alkynes, expanding the utility of this reagent in radical reactions (Ouyang, Xu, and Qing, 2019).
• Low-cost trifluoromethylation reagent: Discusses the economic benefits and wide-ranging applications of trifluoromethanesulfonic anhydride in trifluoromethylation processes (Ouyang, Xu, and Qing, 2018).

アナリシスノート

Assay (acidimetric): ≥ 99.0 %
Density (d 20 °C/ 4 °C): 1.715 - 1.720
Identity (IR): passes test

安全性情報

• ピクトグラム: GHS03,GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H272 - H302 - H314 - H335
• 注意書き: P210 - P220 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1 - Ox. Liq. 2 - Skin Corr. 1B - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 5.1B - Oxidizing hazardous materials
• WGK: WGK 3
• 引火点(°F): not determined
• 引火点(℃): not determined