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由来生物
mouse
品質水準
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
4.1.18, monoclonal
化学種の反応性
human
メーカー／製品名
Chemicon®
テクニック
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
アイソタイプ
IgG1
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... KRT8(3856)
特異性
The antibody reacts with human cytokeratin 8. There is no cross reactivity with human cytokeratin No. 7, 17, 18, or 19. Anti-cytokeratin No. 8 decorates single epithelia in stomach, colon, and small intestine, gall bladder, liver (bile ducts and hepatocytes) as well as pancreatic ducts and mammary gland ducts.
免疫原
Cytoskeletal preparation of MCF-7 cells.
アプリケーション
This Anti-Cytokeratin 8 Antibody, clone 4.1.18 is validated for use in WB, IC, IH, IH(P) for the detection of Cytokeratin 8.
Western blot Immunocytochemistry Immunohistochemistry: Frozen sections, acetone fixed (5-10 μg/mL)
Paraffin sections, after trypsin treatment (5-20 μg/mL)
Optimal-working dilutions must be determined by end user.
Paraffin sections, after trypsin treatment (5-20 μg/mL)
Optimal-working dilutions must be determined by end user.
関連事項
Replaces: 04-588
物理的形状
Format: Purified
Lyophilized from 0.02 M Phosphate buffer, 0.25 M NaCl, pH 7.6 with 0.1% sodium azide.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
10 - Combustible liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MAB3414:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Stanislava Merjava et al.
Investigative ophthalmology & visual science, 52(2), 787-794 (2010-10-12)
The purpose of this study was to investigate the expression of cytokeratin (CK) 8 in the corneoconjunctival epithelium. In 17 cadaveric corneoscleral discs and 3 other discs, the presence of CK8 alone or CK8, together with CK3, CK15, vimentin, and
Leandi Krüger et al.
American journal of physiology. Gastrointestinal and liver physiology, 313(3), G180-G191 (2017-06-03)
Esophageal injury is a risk factor for diseases such as Barrett's esophagus (BE) and esophageal adenocarcinoma. To improve understanding of signaling pathways associated with both normal and abnormal repair, animal models are needed. Traditional rodent models of esophageal repair are
Cristián Vela Hinojosa et al.
PloS one, 8(9), e75062-e75062 (2013-10-03)
The mammary gland has long drawn the attention of the scientific community due to the limited knowledge of some fundamental aspects involved in the control of its function. Myotis velifer, a microchiropteran species, provides an interesting model to study some
Miranda Batchelor et al.
EMBO reports, 5(1), 104-110 (2004-01-08)
While remaining extracellular, enteropathogenic Escherichia coli (EPEC) establish direct links with the cytoskeleton of the target epithelial cell leading to the formation of actin-rich pedestals underneath attached bacteria. The translocated adaptor protein Tir forms the transmembrane bridge between the cytoskeleton
Mathieu Bourdenx et al.
Scientific reports, 7, 45831-45831 (2017-04-05)
Neurodegenerative diseases are characterized by the degeneration of specific brain areas associated with accumulation of disease-related protein in extra- or intra-cellular deposits. Their preclinical investigations are mostly based on genetically-engineered animals. Despite their interest, these models are often based on
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