15209

N,O-ビス(トリメチルシリル)トリフルオロセトアミド および トリメチルクロロシラン

for GC derivatization, LiChropur^™, contains 10% TMCS, 98% (excluding TMCS)

• 別名: BSTFA + TMCS
• 化学式: CF₃C[=NSi(CH₃)₃]OSi(CH₃)₃
• CAS番号: 25561-30-2
• 分子量: 257.40
• Beilstein: 2050024
• MDL番号: MFCD00008269
• UNSPSCコード: 41116105
• PubChem Substance ID: 329750769
• NACRES: NA.22

特性

• グレード: for GC derivatization
• 品質水準: 100
• アッセイ: ≥97.5% (excluding TMCS, GC); 98% (excluding TMCS)
• 形状: liquid
• 品質: LiChropur^™
• 反応適合性: reagent type: derivatization reagent; reaction type: Silylations
• テクニック: gas chromatography (GC): suitable
• 不純物: 9.0-11.0% TMCS
• 屈折率: n20/D 1.384 (lit.)
• bp: 45-50 °C/14 mmHg (lit.)
• 密度: 0.97 g/mL (lit.)
• SMILES記法: C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F
• InChI: 1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+
• InChI Key: XCOBLONWWXQEBS-KPKJPENVSA-N

詳細

詳細

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane has found application to be used in gas chromatography (GC) and mass-spectrometry (MS). It can also be used in HPLC- electrochemical detection assay of 8-oxo-deoxyguanosine and?8-oxo-guanine.

アプリケーション

• Determination of Δ(9)-tetrahydrocannabinol, 11-nor-carboxy-Δ(9)-tetrahydrocannabinol and cannabidiol in human plasma and urine after a commercial cannabidiol oil product intake.: This study uses N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane for derivatization to enhance the sensitivity and accuracy of cannabinoid detection in biological samples. This method is vital for forensic toxicology and clinical research, providing reliable data for cannabinoid analysis (Papoutsis et al., 2024).


• The impact of lipid degradation on fingerprint quality on fired firearm cartridges.: This research employs N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane to study lipid degradation and its effect on fingerprint quality on firearm cartridges. The findings are crucial for forensic science, particularly in improving methods for preserving and analyzing fingerprint evidence (Goulart et al., 2023).


• Contaminants of emerging concern: Silylation procedures, evaluation of the stability of silyl derivatives and associated measurement uncertainty.: This paper evaluates the use of N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane in silylation procedures for environmental analysis. The study assesses the stability and measurement uncertainty of silyl derivatives, which is crucial for accurate monitoring of environmental contaminants (Ljoncheva et al., 2023).


• Screening of Organic Acidurias by Gas Chromatography-Mass Spectrometry (GC-MS).: This research utilizes N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane in the derivatization process for screening organic acidurias. This method is significant for clinical diagnostics, providing a reliable approach for detecting metabolic disorders (Scott et al., 2022).


• A sensitive, robust method for determining natural and synthetic hormones in surface and wastewaters by continuous solid-phase extraction-gas chromatography-mass spectrometry.: The study presents a method using N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane for the detection of hormones in environmental samples. This robust method is essential for monitoring water quality and detecting endocrine-disrupting compounds (Chafi and Ballesteros, 2022).

その他情報

シリル基の位置は明確に特定されていません。N,N および N,Oの両方であると考えられています。

法的情報

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H302,H314
• 注意書き: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 15.8 °F - closed cup
• 引火点(℃): -9 °C - closed cup
• 個人用保護具 (PPE): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter