PHR1331

ジシアンジアミド

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: シアノグアニジン, ジシアノジアミド
• 化学式: NH₂C(=NH)NHCN
• CAS番号: 461-58-5
• 分子量: 84.08
• Beilstein: 605637
• EC Number: 207-312-8
• MDL番号: MFCD00008066
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823316
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to USP 1396310
• APIファミリー: metformin
• CofA: current certificate can be downloaded
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 208-211 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: NC(=N)NC#N
• InChI: 1S/C2H4N4/c3-1-6-2(4)5/h(H4,4,5,6)
• InChI Key: QGBSISYHAICWAH-UHFFFAOYSA-N

詳細

詳細

品質管理の認定を受けた製品番号医薬品の2次標準は、薬局方の1次標準に対する便利で対費用効果の高い代替品を医薬品研究室と製薬企業に提供します。

アプリケーション

This pharmaceutical secondary standard can also be used as follows:

• Separation and estimation of metformin along with other antidiabetics from meglitinides class in the presence of metformin impurity cyanoguanidine using a liquid chromatography method in pharmaceutical formulations
• Development of a reversed phase-high performance liquid chromatographic (RP-HPLC) method combined with a UV-diode array detector (PDA) for the impurity analysis of combined dosage tablet of metformin hydrochloride and teneligliptin hydrobromide hydrate
• Estimation of empagliflozin, linagliptin, along with metformin and its related impurities cyanoguanidine and melamine using HPLC-DAD and high-performance thin layer chromatography (HPTLC) methods in their combined tablets
• Development and validation of a stability indicating capillary zone electrophoresis (CZE) method for the quantification of metformin and its major impurity in pharmaceutical formulation
• Simultaneous determination of vildagliptin, metformin, and metformin-related compounds (A, B, and C) in tablets using a high-performance liquid chromatography-tandem mass spectrometry method (HPLC-MS/MS)

アナリシスノート

このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。

脚注

To see an example of a Certificate of Analysis for this material enter LRAA0834 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable