B1651

ブラジキニンフラグメント 1-7

≥97% (HPLC)

• 別名: 1-7-Bradykinin
• 実験式（ヒル表記法）: C₃₅H₅₂N₁₀O₉
• CAS番号: 23815-87-4
• 分子量: 756.85
• MDL番号: MFCD00076262
• UNSPSCコード: 12352209
• PubChem Substance ID: 24891606
• NACRES: NA.26

特性

• 製品名: ブラジキニンフラグメント 1-7, ≥97% (HPLC)
• 品質水準: 200
• アッセイ: ≥97% (HPLC)
• フォーム: powder
• 色: white
• UniProtアクセッション番号: P01161
• 保管温度: −20°C
• SMILES記法: NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(O)=O
• InChI: 1S/C35H52N10O9/c36-22(10-4-14-39-35(37)38)31(50)44-16-6-12-26(44)33(52)43-15-5-11-25(43)30(49)40-19-28(47)41-23(18-21-8-2-1-3-9-21)29(48)42-24(20-46)32(51)45-17-7-13-27(45)34(53)54/h1-3,8-9,22-27,46H,4-7,10-20,36H2,(H,40,49)(H,41,47)(H,42,48)(H,53,54)(H4,37,38,39)
• InChI Key: CRROPKNGCGVIOG-UHFFFAOYSA-N
• 遺伝子情報: rat ... Nppa(24602)

詳細

Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro

詳細

Bradykinin fragment 1-7 (BK-(1-7)), an endogenous peptide, is present in plasma.

アプリケーション

Bradykinin Fragment 1-7 has been used as an external calibrant/standard in the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis of protein spots.

Bradykinin Fragment 1-7 is used in research on the specificity and kinetics of kininase(s).

生物化学的／生理学的作用

Bradykinin (BK) is a pro-inflammatory mediator and a neuromediator. It modulates several vascular and renal functions. Bradykinin (BK) plays a key role in inducing vascular permeability and mitogenesis. It helps to activate the liberation of nitric oxide in inflammatory and cancer tissues.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)