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Merck

M2650

Sigma-Aldrich

抗マウスIgG (Fc特異的) ヤギ宿主抗体

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

goat

品質水準

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

secondary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

テクニック

indirect ELISA: 1:15,000

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

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詳細

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. A immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin. It consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.

特異性

Binds mouse IgG; does not bind other mouse Igs.

アプリケーション

Anti-Mouse IgG (Fc specific) antibody produced in goat has been used in enzyme linked immunosorbent assay (ELISA), immunofluorescence analysis/fluorescence activated cell sorting (FACS) analysis.

生物化学的/生理学的作用

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. It mainly helps in immune defense. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

その他情報

本抗体は、ヒトIgGで吸収済です。

物理的形状

0.01M PBS溶液 (pH 7.4, 15mMアジ化ナトリウム含有)

調製ノート

ヒトサンプルでのバックグラウンド低減のため吸収処理済み。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

M2650-VAR:
M2650-BULK:
M2650-1ML:


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文書ライブラリにアクセスする

Joan Puñet-Ortiz et al.
Frontiers in immunology, 9, 2661-2661 (2018-12-07)
Sjögren's Syndrome (SjS) is a common chronic autoimmune disease characterized by the B cell hyperactivation, lymphocyte infiltration, and tissue damage of exocrine glands. It can also present life-threatening extraglandular manifestations, such as pulmonary and hepatic involvement, renal inflammation and marginal
Max Y Chen et al.
Bio-protocol, 13(11), e4689-e4689 (2023-06-16)
Cell populations and tissues exhibit unique gene expression profiles, which allow for characterizing and distinguishing cellular subtypes. Monitoring gene expression of cell type-specific markers can indicate cell status such as proliferation, stress, quiescence, or maturation. Quantitative reverse transcriptase PCR (qRT-PCR)
Navaneetha Krishnan Bharathan et al.
Nature cell biology, 25(6), 823-835 (2023-06-09)
The endoplasmic reticulum (ER) forms a dynamic network that contacts other cellular membranes to regulate stress responses, calcium signalling and lipid transfer. Here, using high-resolution volume electron microscopy, we find that the ER forms a previously unknown association with keratin
Amado Carreras-Sureda et al.
Human molecular genetics, 22(3), 519-530 (2012-10-27)
T lymphocytes rely on a Ca(2+) signal known as store-operated calcium entry (SOCE) for their activation. This Ca(2+) signal is generated by activation of a T-cell receptor, depletion of endoplasmic reticulum (ER) Ca(2+) stores and activation of Ca(2+) release-activated Ca(2+)
Enhancement of beta-glucosidase stability and cellobiose-usage using surface-engineered recombinant Saccharomyces cerevisiae in ethanol production
Pack SP, et al.
Biotechnology Letters, 24(22), 1919-1925 (2002)

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