S9637
コハク酸ナトリウム 二塩基性 六水和物
BioReagent, suitable for cell culture, suitable for insect cell culture
別名:
コハク酸 二ナトリウム塩, ブタン二酸 二ナトリウム塩
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About This Item
化学式:
NaOOCCH2CH2COONa · 6H2O
CAS番号:
分子量:
270.14
Beilstein:
3921044
EC Number:
MDL番号:
UNSPSCコード:
12352207
PubChem Substance ID:
NACRES:
NA.71
溶解性:
H2O: 100 mg/mL, clear, colorless
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製品種目
BioReagent
品質水準
テクニック
cell culture | insect: suitable
cell culture | mammalian: suitable
pH
8—9.5 (25 °C, 270 g/L)
溶解性
H2O: 100 mg/mL, clear, colorless
SMILES記法
O.O.O.O.O.O.[Na+].[Na+].[O-]C(=O)CCC([O-])=O
InChI
1S/C4H6O4.2Na.6H2O/c5-3(6)1-2-4(7)8;;;;;;;;/h1-2H2,(H,5,6)(H,7,8);;;6*1H2/q;2*+1;;;;;;/p-2
InChI Key
ZBTUYCUNQBRXOR-UHFFFAOYSA-L
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詳細
Sodium succinate dibasic hexahydrate is the sodium salt of succinic acid, a dicarboxylic acid. This versatile compound finds extensive use in cell biology, cell culture, and biochemical research applications. It serves as both an energy source and a buffer in cell culture and cell biology research, particularly within the Tricarboxylic Acid (TCA) or Krebs cycle. It is hypothesized that Sodium succinate dibasic hexahydrate acts as an ionophore, facilitating the transport of ions across cell membranes and thus influencing cellular metabolism. Also known as Succinic acid disodium salt, this product provides the necessary substrate for ATP (adenosine triphosphate) production, essential for optimal cellular function.
アプリケーション
Sodium succinate dibasic hexahydrate has been used:
- as a supplement in the assay medium to incubate mitochondria to measure the specific activity of complex-II
- as a component in plant induction medium/ protoplast induction media (PIM) for plant regeneration
- as a small-molecule additive in the fresh medium to study its positive synergistic effects on transgene expression in Chinese hamster ovary (CHO) cells
特徴および利点
- Versatile and adaptable for a wide variety of laboratory and research applications
- BioReagent Grade Sodium succinate for your Cell Biology and Biochemical research
- Tested for Mammalian and Insect cell culture applications
その他情報
For additional information on our range of Biochemicals, please complete this form.
保管分類コード
11 - Combustible Solids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
S9637-1KG:
S9637-BULK:
S9637-500G:
S9637-VAR:
S9637-100G:
最新バージョンのいずれかを選択してください：
試験成績書（COA）
Lot/Batch Number
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Huimin Mao et al.
Stem cells international, 2020, 2016809-2016809 (2020-03-28)
Most mesenchymal stem cells reside in a niche of low oxygen tension. Iron-chelating agents such as CoCl2 and deferoxamine have been utilized to mimic hypoxia and promote cell growth. The purpose of the present study was to explore whether a
Wei-Feng Li et al.
New biotechnology, 69, 8-17 (2022-02-27)
Chinese hamster ovary (CHO) cells are currently the most widely used host cells for production of recombinant therapeutic proteins (RTPs). Small-molecule additives related to cell cycle apoptosis and autophagy regulation have been used to promote RTP production. By combining two
Jongjin Park et al.
Methods in molecular biology (Clifton, N.J.), 1917, 337-354 (2019-01-06)
CRISPR/Cas9 nuclease system is getting popular in precise genome editing of both eukaryotic and prokaryotic systems due to its accuracy, programmability, and relative ease of use. CRISPR/Cas systems can be delivered into live cells via plasmid DNA, RNA, and ribonucleoprotein
Georgia L Isom et al.
Cell, 181(3), 653-664 (2020-05-04)
Gram-negative bacteria are surrounded by an outer membrane composed of phospholipids and lipopolysaccharide, which acts as a barrier and contributes to antibiotic resistance. The systems that mediate phospholipid trafficking across the periplasm, such as MCE (Mammalian Cell Entry) transporters, have
Adrián Povo-Retana et al.
Cancers, 12(10) (2020-10-24)
Tumor-associated macrophages (TAMs) play a crucial role in suppressing the immunosurveillance function of the immune system that prevents tumor growth. Indeed, macrophages can also be targeted by different chemotherapeutic agents improving the action over immune checkpoints to fight cancer. Here
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