SML1087

Sumanirole maleate

≥98% (HPLC)

• 別名: (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, CID 9818479 maleate, PNU-95,666 maleate
• 実験式（ヒル表記法）: C₁₁H₁₃N₃O · C₄H₄O₄
• CAS番号: 179386-44-8
• 分子量: 319.31
• MDL番号: MFCD09832637
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825464
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 光学活性: [α]/D -22 to -32°, c = 1 in H₂O
• 保管条件: desiccated
• 色: white to beige
• 溶解性: H₂O: 10 mg/mL, clear
• 保管温度: −20°C
• SMILES記法: O=C1N(C[C@H](NC)C2)C3=C2C=CC=C3N1.O=C(O)/C=C\C(O)=O
• InChI: 1S/C11H13N3O.C4H4O4/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9;5-3(6)1-2-4(7)8/h2-4,8,12H,5-6H2,1H3,(H,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m1./s1
• InChI Key: VOJRMYBBPKNLLI-ORHWHDKWSA-N

詳細

アプリケーション

Sumanirole maleate has been used as a dopamine type 2 receptor (D2R) agonist to study its effects on spatial learning and memory in rats.

生物化学的／生理学的作用

Sumanirole is a highly selective and potent dopamine D2 receptor agonist that decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta. Sumanirole potently stimulates locomotor activity in in animal models of Parkinson′s disease.

特徴および利点

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable