콘텐츠로 건너뛰기
Merck
모든 사진(1)

주요 문서

모든 문서 보기

906301

Sigma-Aldrich

BTTES

동의어(들):

3-(4-((Bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)propane-1-sulfonic acid, Copper click-chemistry ligand, Water-soluble CuAAC ligand

로그인조직 및 계약 가격 보기
모든 사진(1)

About This Item

실험식(Hill 표기법):
C20H34N10O3S
CAS Number:
2101505-88-6
Molecular Weight:
494.61
UNSPSC 코드:
12161600

형태

solid

반응 적합성

reaction type: click chemistry

재고 정보

available only in USA

저장 온도

2-8°C

관련 카테고리

애플리케이션

BTTES is a a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTES are advancements from water-insoluble TBTA and are desirable for bioconjugation in diverse chemical biology experiments.

기타 정보

Sulfated Ligands for the Copper(I)-Catalyzed Azide-Alkyne Cycloaddition

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study

Biocompatible copper(I) catalysts for in vivo imaging of glycans

관련 제품

제품 번호
설명
가격

픽토그램

Flame
GHS02

신호어

Danger

유해 및 위험 성명서

H242

Hazard Classifications

Self-react. C

Storage Class Code

5.2 - Organic peroxides and self-reacting hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
MKCT5381
MKCQ3415
MKCJ8732

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Wei Wang et al.
Chemistry, an Asian journal, 6(10), 2796-2802 (2011-09-10)
The copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), the prototypical reaction of click chemistry, is accelerated by tris(triazolylmethyl)amine-based ligands. Herein, we compare two new ligands in this family--3-[4-({bis[(1-tert-butyl-1H-1,2,3-triazol-4-yl)methyl]amino}methyl)-1H-1,2,3-triazol-1-yl]propanol (BTTP) and the corresponding sulfated ligand 3-[4-({bis[(1-tert-butyl-1H-1,2,3-triazol-4-yl)methyl]amino}methyl)-1H-1,2,3-triazol-1-yl]propyl hydrogen sulfate (BTTPS)--for three bioconjugation applications: 1) labeling
David Soriano Del Amo et al.
Journal of the American Chemical Society, 132(47), 16893-16899 (2010-11-11)
The Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) is the standard method for bioorthogonal conjugation. However, current Cu(I) catalyst formulations are toxic, hindering their use in living systems. Here we report that BTTES, a tris(triazolylmethyl)amine-based ligand for Cu(I), promotes the cycloaddition reaction rapidly
Christen Besanceney-Webler et al.
Angewandte Chemie (International ed. in English), 50(35), 8051-8056 (2011-07-16)
Raising the bar: the efficacy of bioorthogonal reactions for bioconjugation has been thoroughly evaluated in four different biological settings. Powered by the development of new biocompatible ligands, the copper-catalyzed azide-alkyne cycloaddition has brought about unsurpassed bioconjugation efficiency, and thus it

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.